Vitamin D3

Suppliers

Names

[ CAS No. ]:
67-97-0

[ Name ]:
Vitamin D3

[Synonym ]:
Oxarol
Vitamin D3
Ebivit
Cholecalciferolum
(3S,5Z,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(1S,3Z)-3-[(2E)-2-{(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]-7a-methyloctahydro-4H-inden-4-yliden}ethyliden]-4-methylidencyclohexanol
Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
Micro-Dee
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
Deparal
FeraCol
MFCD00078131
9,10-secocholesta-5,7,10-trien-3-ol, (3S,5Z,7E)-
Prezios
cholecalciferol
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol
UNII-1C6V77QF41
Vi-De3
MC 1275
Granuvit D3
Devaron
(3b,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-(1,5-dimethylhexyl)octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
rampage
vitamin D3 powder
D3-Vicotrat
NEO Dohyfral D3
(1S,3Z)-3-[(2E)-2-{(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexanol
Vigantol
EINECS 200-673-2
9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3β,5Z,7E)-
(1S,3Z)-4-Methylene-3-[(2E)-2-{(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methyl-2-heptanyl]octahydro-4H-inden-4-ylidene}ethylidene]cyclohexanol
colecalciferol
Videkhol
(3β,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
[3H]-Vitamin D3
9,10-Secocholesta-5,7,10(19)-trien-3b-ol
calciol
Provitina
VITAMIN D

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
496.4±24.0 °C at 760 mmHg

[ Melting Point ]:
83-86 °C(lit.)

[ Molecular Formula ]:
C₂₇H₄₄O

[ Molecular Weight ]:
384.638

[ Flash Point ]:
214.2±15.1 °C

[ Exact Mass ]:
384.339203

[ PSA ]:
20.23000

[ LogP ]:
9.72

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.523

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VS2900000

CHEMICAL NAME :: 9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol

CAS REGISTRY NUMBER :: 67-97-0

LAST UPDATED :: 199701

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C27-H44-O

MOLECULAR WEIGHT :: 384.71

WISWESSER LINE NOTATION :: L56 FYTJ A1 BY1&3Y1&1 FU2U- BL6YYTJ AU1 DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - infant

DOSE/DURATION :: 39 mg/kg/34W-I

TOXIC EFFECTS :: Behavioral - anorexia (human) Behavioral - irritability Gastrointestinal - decreased motility or constipation

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 295,1173,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 43,125,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 43(255-256),14,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 136 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 31,105,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Gastrointestinal - other changes

REFERENCE :: JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915- Volume(issue)/page/year: 193,211,1988 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 90 mg/kg

SEX/DURATION :: female 12-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

REFERENCE :: FOMOAJ Folia Morphologica (Warsaw). (Panstwowy Zaklad Wydawnictw Lekarskich, ul. Dluga 38-40, 00 238 Warsaw, Poland) V.1- 1929- Volume(issue)/page/year: 29,333,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80574 No. of Facilities: 179 (estimated) No. of Industries: 4 No. of Occupations: 18 No. of Employees: 6614 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80574 No. of Facilities: 2284 (estimated) No. of Industries: 12 No. of Occupations: 36 No. of Employees: 85071 (estimated) No. of Female Employees: 59178 (estimated)

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311-H330-H372

[ Precautionary Statements ]:
P260-P280-P284-P301 + P310-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R24/25;R26;R48/25

[ Safety Phrases ]:
S28-S36/37-S45-S28A

[ RIDADR ]:
UN 2811 6.1/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
VS2900000

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2936240000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Vitamin D3
tert-Butyl Hydroperoxide
vitamin D3 palmitate
tert-Butyl-{3-[2-(diphenyl-phosphinoyl)-ethylidene]-4-methylene-cyclohexyloxy}-dimethyl-silane
{[(3Z)-3-(2-Chloroethylidene)-4-methylenecyclohexyl]oxy}(dimethyl )(2-methyl-2-propanyl)silane
Calcifediol

Customs

[ HS Code ]: 2936240000

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