Fenoldopam (mesylate)

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Names

[ CAS No. ]:
67227-57-0

[ Name ]:
Fenoldopam (mesylate)

[Synonym ]:
EINECS 266-612-7
Fenoldopam monomethanesulfonate
MFCD04112986
6-Chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-(p-hydroxyphenyl)-1H-3-benzazepinium methanesulphonate
Corlopam
Fenoldopam methanesulfonate
6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate
9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Fenoldopam mesylate
6-chloro-7,8-dihydroxy-1-(p-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine methanesulfonate
6-chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl)-1H-3-benzazepine-7,8-diol methanesulfonate
CORLOPAM MESYLATE
Fenoldopam (mesylate)

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
522.6ºC at 760 mmHg

[ Molecular Formula ]:
C17H20ClNO6S

[ Molecular Weight ]:
401.86

[ Flash Point ]:
269.9ºC

[ PSA ]:
104.24000

[ LogP ]:
3.77680

[ Storage condition ]:
room temp

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317-H319

[ Precautionary Statements ]:
P280-P301 + P312 + P330-P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36-42/43

[ Safety Phrases ]:
22-26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • Methanesulfonic acid
  • Fenoldopam

DownStream

Articles

The role of eNOS phosphorylation in causing drug-induced vascular injury.

Toxicol. Pathol. 42(4) , 709-724, (2014)

Previously we found that regulation of eNOS is an important part of the pathogenic process of Drug-induced vascular injury (DIVI) for PDE4i. The aims of the current study were to examine the phosphory...

In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells.

Gene Ther. 22 , 947-59, (2015)

Oncolytic viruses (OV) have broad potential as an adjuvant for the treatment of solid tumors. The present study addresses the feasibility of clinically applicable drugs to enhance the oncolytic potent...

Contrast-induced nephropathy: protective role of fenoldopam.

Clin. Exp. Pharmacol. Physiol. 39(6) , 497-505, (2012)

1. Contrast-induced nephropathy (CIN) often occurs after contrast media-related procedures and is associated with increased morbidity and mortality. The acute renal failure observed after administrati...


More Articles


Related Compounds

  • Fenoldopam-d4 mesylate
  • Fenoldopam
  • Fenoldopam hydrobromide
  • Fenoldopam hydrochloride
  • BPR1R024 mesylate
  • Tropisetron mesylate