(R)-1-(4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Cyclohexyl)-N-((R)-1-Phenylethyl)Ethanamine

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Names

[ CAS No. ]:
672314-45-3

[ Name ]:
(R)-1-(4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Cyclohexyl)-N-((R)-1-Phenylethyl)Ethanamine

[Synonym ]:
(1S)-1-[4-({[Dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)cycloh exyl]-N-[(1S)-1-phenylethyl]ethanamine

Chemical & Physical Properties

[ Molecular Formula ]:
C23H41NOSi

[ Molecular Weight ]:
375.66300

[ Exact Mass ]:
375.29600

[ PSA ]:
21.26000

[ LogP ]:
6.94480

Synthetic Route

Precursor & DownStream

Precursor

  • METHYLMAGNESIUM BROMIDE
  • (R)-N-[(4'-tert-butyldimethylsilyloxymethyl-cyclohexyl)methylidene]-1-phenylethanamine
  • Cyclohexane-1,4-dimethanol
  • (R)-(+)-1-Phenylethylamine
  • tert-Butyldimethylsilyl chloride
  • (4-(((Tert-Butyldimethylsilyl)Oxy)Methyl)Cyclohexyl)Methanol
  • 4-(tert-butyldimethylsilanyloxymethyl)-cyclohexanecarbaldehyde

DownStream

  • N-Boc-Y-27632
  • (R)-1-[4-(tert-Butyldimethylsilyloxymethyl)cyclohexyl]ethan-1-amine
  • (R)-N-Boc-1-[4-(tert-butyldimethylsilyloxymethyl)cyclohexyl]ethan-1-amine