Fenoldopam hydrobromide

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Names

[ CAS No. ]:
67287-54-1

[ Name ]:
Fenoldopam hydrobromide

[Synonym ]:
EINECS 266-634-7
9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol,hydrobromide

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
522.6ºC at 760 mmHg

[ Molecular Formula ]:
C16H17BrClNO3

[ Molecular Weight ]:
386.66800

[ Flash Point ]:
269.9ºC

[ Exact Mass ]:
385.00800

[ PSA ]:
72.72000

[ LogP ]:
4.02130

MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H319-H334

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22;R36;R42/43

[ Safety Phrases ]:
S22;S26;S36/S37/S39

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-2-(2-chloro-3,4-dimethoxyphenyl)ethylamine
  • 6-Chloro-2,3,4,5-tetrahydro-7,8-dimethoxy-1-(4-methoxyphenyl)-1H-3-benzazepine
  • Isovanillin
  • 2-chloro-1-(chloromethyl)-3,4-dimethoxybenzene
  • 2-Chloro-3,4-dimethoxybenzaldehyde
  • 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
  • 2-(2-Chloro-3,4-dimethoxyphenyl) ethylamine
  • (2-chloro-3,4-dimethoxyphenyl)acetonitrile
  • (2-Chloro-3,4-dimethoxyphenyl)methanol
  • 4-Methoxystyrene

DownStream

  • Fenoldopam

Articles

Chemical genetics reveals a complex functional ground state of neural stem cells.

Nat. Chem. Biol. 3(5) , 268-273, (2007)

The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nat. Chem. Biol. 5 , 765-71, (2009)

Studies of gene function and molecular mechanisms in Plasmodium falciparum are hampered by difficulties in characterizing and measuring phenotypic differences between individual parasites. We screened...

Contrast-induced nephropathy: protective role of fenoldopam.

Clin. Exp. Pharmacol. Physiol. 39(6) , 497-505, (2012)

1. Contrast-induced nephropathy (CIN) often occurs after contrast media-related procedures and is associated with increased morbidity and mortality. The acute renal failure observed after administrati...


More Articles


Related Compounds

  • Fenoldopam
  • Fenoldopam (mesylate)
  • Fenoldopam-d4 mesylate
  • Fenoldopam hydrochloride
  • Xylopropamine Hydrobromide
  • Scopolamine hydrobromide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Tert-butyl 9-(5-methylfuran-3-yl)-5-oxa-2,8-diazaspiro[3.5]nonane-2-carboxylate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide