D-phenylalanine

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Names

[ CAS No. ]:
673-06-3

[ Name ]:
D-phenylalanine

[Synonym ]:
(S)-phenylalanine
L-Phenylalanine
H-D-Phe-OH
(2S)-2-amino-3-phenylpropanoic acid
L-PHENYLALININE
α-Amino-β-phenylpropionic acid, L-
H-Phe-OH
Alanine, 3-phenyl-
L-phenylalanine zwitterion
S-phenylalanine
D-b-Phenylalanine
D-β-Phenylalanine
(S)-(-)-Phenylalanine
(R)-Phenylalanine
(S)-a-Amino-b-phenylpropionic Acid
Alanine, phenyl-, L-
L-2-Amino-3-phenylpropionic acid
(S)-2-Amino-3-phenylpropionic acid
(S)-2-Amino-3-phenylpropanoic acid
D-a-Amino-b-phenylpropionic Acid
C6H5CH2CH(NH2)COOH
(S)-a-Aminohydrocinnamic Acid
D-α-Amino-β-phenylpropionic acid
Phenylalanine
α-Aminohydrocinnamic acid, L-
(L)-Phenylalanine
Phenylalanine (VAN)
Phenylalanine, L-
phenylalanine D-form
Benzenepropanoic acid, α-amino-, (S)-
l-Phe
EINECS 211-603-5
PhE
D-phenylalanine zwitterion
β-phenyl-L-alanine
d-Phe
(-)-Phenylalanine
(S)-α-Aminobenzenepropanoic acid
MFCD00004270
(R)-(+)-Phenylalanine
α-Amino-β-phenylpropionic acid
(2R)-2-amino-3-phenylpropanoic acid
(S)-A-Aminobenzenepropanoic Acid
D-Phenylalanine
D-alpha-Amino-beta-phenylpropionic acid

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
307.5±30.0 °C at 760 mmHg

[ Melting Point ]:
273-276 °C(lit.)

[ Molecular Formula ]:
C9H11NO2

[ Molecular Weight ]:
165.189

[ Flash Point ]:
139.8±24.6 °C

[ Exact Mass ]:
165.078979

[ PSA ]:
63.32000

[ LogP ]:
1.11

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Water Solubility ]:
27 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY7533000
CHEMICAL NAME :
Alanine, phenyl-, D-
CAS REGISTRY NUMBER :
673-06-3
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C9-H11-N-O2
MOLECULAR WEIGHT :
165.21
WISWESSER LINE NOTATION :
QVYZ1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
500 mg/kg/5W-I
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 1(3),124,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5452 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 64,319,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5535 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 307 (estimated) No. of Female Employees: 251 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AY7533000

[ HS Code ]:
29224995

Synthetic Route

Precursor & DownStream

Precursor

  • (3R,5R,6S)-4-(benzyloxycarbonyl)-5,6-diphenyl-3-(phenylmethyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one
  • D-α-Hydrazino-β-phenyl-propionsaeure
  • aloc-d-phe-oh dcha
  • (+)-tert-butyl N-Boc-phenylalaninate
  • DL-Phenylalanine
  • Benzyl bromide
  • Glycine

DownStream

  • D-Phenylalanine,N-(2,4-dinitrophenyl)-
  • H-D-Phe-Obut HCl
  • n-formyl-d-phenylalanine
  • D-phenylalaninol
  • h-d-cha-oh hcl
  • a-methyl-D-phenylalanine
  • (3R)-1,2,3,4-tetrahydroisoquinolin-2-ium-3-carboxylate
  • 2-[(4-chlorophenyl)sulfonylamino]-3-phenylpropanoic acid
  • (R)-3-ACETYL-4-BENZYLOXAZOLIDIN-2-ONE
  • Fmoc-D-Phe-OH

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • D-Phenylalanine-d8
  • D-Phenylalanine ethyl
  • D-Phenylalanine methyl
  • formyl-D-phenylalanine
  • Dansyl-D-phenylalanine
  • 4-Ethyl-D-phenylalanine
  • 1-((3-(Benzyloxy)phenyl)amino)-7,8,9,10-tetrahydrobenzo[c][1,8]naphthyridin-6(5h)-one
  • 1-(4-Amino-phenoxy)-7,8,9,10-tetrahydro-5H-benzo[c][1,8]naphthyridin-6-one
  • 2-(2-benzyl-5-methyl-2H-pyrazol-3-yl)-ethanol
  • tert-butyl N-[2-(2-nitrobenzenesulfonamido)ethyl]carbamate
  • Carbamic acid, (3-azido-2-methylpropyl)-, 1,1-dimethylethyl ester, (S)-
  • tert-butyl N-[(2R)-1-azidopropan-2-yl]carbamate
  • n-(5-Bromothiazolo[5,4-b]pyridin-2-yl)nicotinamide
  • 1,3-Dibromo-5-iodo-2-methoxybenzene
  • 6-amino-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
  • 2-chloro-5-(1-methyl-1H-pyrazol-4-yl)nicotinonitrile
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