2,3,7,8-tetrabromodibenzofuran

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Names

[ Name ]:
2,3,7,8-tetrabromodibenzofuran

[Synonym ]:
2,3,7,8-tetrabromobenzofuran
2,3,7,8-tetrabromo-dibenzofuran
2,3,7,8-Tetrabrom-dibenzofuran
Dibenzofuran,2,3,7,8-tetrabromo

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₄Br₄O

[ Molecular Weight ]:
483.77600

[ Exact Mass ]:
479.70000

[ PSA ]:
13.14000

[ LogP ]:
6.63600

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HP5295170

CHEMICAL NAME :: Dibenzofuran, 2,3,7,8-tetrabromo-

CAS REGISTRY NUMBER :: 67733-57-7

BEILSTEIN REFERENCE NO. :: 0221403

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H4-Br4-O

MOLECULAR WEIGHT :: 483.80

WISWESSER LINE NOTATION :: T B656 HOJ DE EE KE LE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4740 ng/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 320,151,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 ug/kg

SEX/DURATION :: female 10-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 107,141,1991

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 ug/kg

SEX/DURATION :: female 10-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 107,141,1991

Related Compounds

2,3,7,8-TETRAMETHYL-1,4,6,9-THIANTHRENETETRONE
2,3,7,8,12,13,17,18-OCTAETHYL-21H,23H-PORPHINE MANGANESE(III) CHLORIDE
2,3,7,8,12,13,17,18-Octaethyl-21H,23Hporphine ruthenium(II)carbonyl
2,3,7,8-tetramethoxy-10,11-dihydro-5H-10,5-azaethano-dibenzo[a,d]cycloheptene
2,3,7,8-tetramethoxyselenanthrene
2,3,7,8-tetrachlorodibenzo-p-dioxin-1-ol
4-bromo-N-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)thiophene-2-carboxamide
2-bromo-N-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)benzamide
5-chloro-N-(3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)-1H-indole-2-carboxamide
1-(4-fluorophenyl)-5-methyl-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)-1H-1,2,3-triazole-4-carboxamide
N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)-3-(3-(o-tolyl)-1,2,4-oxadiazol-5-yl)propanamide
4-isopropoxy-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)benzamide
1-(4-chlorophenyl)-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)cyclopentanecarboxamide
1-methyl-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)-1H-1,2,3-triazole-4-carboxamide
3-(3-chlorophenyl)-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)propanamide
6-isopropoxy-N-(2-methyl-3-oxo-2,3,5,6,7,8-hexahydrocinnolin-6-yl)nicotinamide

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