iCRT-14

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Names

[ CAS No. ]:
677331-12-3

[ Name ]:
iCRT-14

[Synonym ]:
iCRT14
iCRT 14

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₇N₃O₂S

[ Molecular Weight ]:
375.44400

[ Exact Mass ]:
375.10400

[ PSA ]:
80.50000

[ LogP ]:
4.79500

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ RIDADR ]:
NONH for all modes of transport

Articles

Sequential actions of β-catenin and Bmp pattern the oral nerve net in Nematostella vectensis.

Nat. Commun. 5 , 5536, (2014)

Animal evolution is closely linked to the emergence of the nervous system. At present it is unknown how the basic mechanisms of neural induction and formation of central nervous systems evolved. We ad...

A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells.

Stem Cells 32(12) , 3196-208, (2014)

Wnt/β-catenin signaling is essential for neurogenesis but less is known about β-catenin-independent Wnt signals. We show here that Wnt/activator protein-1 (AP-1) signaling drives differentiation of hu...

Targeting Wnt pathway in mantle cell lymphoma-initiating cells.

J. Hematol. Oncol. 8 , 63, (2015)

Mantle cell lymphoma (MCL) is an aggressive and incurable form of non-Hodgkin's lymphoma. Despite initial intense chemotherapy, up to 50% of cases of MCL relapse often in a chemoresistant form. We hyp...