Norverapamil hydrochloride

Names

[ Name ]:
Norverapamil hydrochloride

[Synonym ]:
N-Nor-(+/-)-verapamil hydrochloride
Nor Verapamil Hydrochloride
Norverapamil hydrochloride
Norverapamil (hydrochloride)

Chemical & Physical Properties

[ Melting Point ]:
155-160â„ƒ dec.

[ Molecular Formula ]:
C₂₆H₃₇ClN₂O₄

[ Molecular Weight ]:
477.04

[ LogP ]:
2.02400

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P301 + P312 + P330-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
UN 2811 6.1/PG 3

Articles

Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs.

J. Infect. Dis. 210(3) , 456-66, (2014)

Drug tolerance likely represents an important barrier to tuberculosis treatment shortening. We previously implicated the Mycobacterium tuberculosis efflux pump Rv1258c as mediating macrophage-induced ...

Application of permeability-limited physiologically-based pharmacokinetic models: part II - prediction of P-glycoprotein mediated drug-drug interactions with digoxin.

J. Pharm. Sci. 102(9) , 3161-73, (2013)

Digoxin is the recommended substrate for assessment of P-glycoprotein (P-gp)-mediated drug-drug interactions (DDIs) in vivo. The overall aim of our study was to investigate the inhibitory potential of...

Stereoselective CZE method for analysis of verapamil and norverapamil in human plasma.

Acta Pol. Pharm. 70(3) , 395-401, (2013)

A stereospecific capillary zone electrophoresis (CZE) method was developed for the determination of verapamil (VER) and its main metabolite norverapamil (NOR) in human plasma. Optimal temperature, cyc...

Norverapamil hydrochloride

Suppliers

Names

Chemical & Physical Properties

MSDS

Click to get detail MSDS

Safety Information

Articles

Related Compounds