Sodium citrate

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Names

[ CAS No. ]:
68-04-2

[ Name ]:
Sodium citrate

[Synonym ]:
FEMA 3026
trisodium citrate
anhydrous sodium citrate
Na3-citrate
citnatin
citrosodna
citrosodina
MFCD00012462
natrocitral
citric acid trisodium salt
citreme
citrosodine
anhydrous trisodium citrate
Citric acid 3Na
EINECS 200-675-3

Chemical & Physical Properties

[ Density]:
1.008 g/mL at 20 °C

[ Melting Point ]:
300°C

[ Molecular Formula ]:
C₆H₅Na₃O₇

[ Molecular Weight ]:
258.069

[ Exact Mass ]:
257.972839

[ PSA ]:
140.62000

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GE8300000

CHEMICAL NAME :: Citric acid, trisodium salt

CAS REGISTRY NUMBER :: 68-04-2

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C6-H5-O7.3Na

MOLECULAR WEIGHT :: 258.08

WISWESSER LINE NOTATION :: QV1XQVQ1VQ &-NA- 3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1548 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1364 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 449 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,65,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 68905 No. of Facilities: 38675 (estimated) No. of Industries: 165 No. of Occupations: 97 No. of Employees: 200416 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0257 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 68905 No. of Facilities: 13473 (estimated) No. of Industries: 96 No. of Occupations: 105 No. of Employees: 301805 (estimated) No. of Female Employees: 163142 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi,C

[ Risk Phrases ]:
R22:Harmful if swallowed. R40:Limited evidence of a carcinogenic effect. R48/20/22:Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed .

[ Safety Phrases ]:
S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
GE8300000

[ HS Code ]:
2918150000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Zinc citrate dihydrate
(E)-Aconitic Acid
L-glutamic acid
L-(-)-Malic acid
Tricarballylic acid
Calcium citrate tetrahydrate
Sodium citrate dihydrate
trisilver citrate
Gold

Customs

[ HS Code ]: 2918150000

[ Summary ]:
2918150000. other salts and esters of citric acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:4ABXY(export license,certificate of inspection for goods inward,certificate of inspection for goods outwardexport license(processing trade),export license(border small volume trade)). MFN tariff:6.5%. General tariff:30.0%

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