Benziodarone

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Names

[ CAS No. ]:
68-90-6

[ Name ]:
Benziodarone

[Synonym ]:
Corofam
Amplivix
Cardivix
Coronal-crinos
Benziodaron
Algocor
Dila-Vasal
Retrangor
BENZIODARONE
Dilafurane

Chemical & Physical Properties

[ Density]:
1.993g/cm3

[ Boiling Point ]:
518.2ºC at 760 mmHg

[ Melting Point ]:
166 °C

[ Molecular Formula ]:
C₁₇H₁₂I₂O₃

[ Molecular Weight ]:
518.08400

[ Flash Point ]:
267.2ºC

[ Exact Mass ]:
517.88800

[ PSA ]:
50.44000

[ LogP ]:
5.14100

[ Index of Refraction ]:
1.727

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OB1835000

CHEMICAL NAME :: Ketone, 3,5-diiodo-4-hydroxyphenyl 2-ethyl-3-benzofuranyl

CAS REGISTRY NUMBER :: 68-90-6

BEILSTEIN REFERENCE NO. :: 1257683

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C17-H12-I2-O3

MOLECULAR WEIGHT :: 518.09

WISWESSER LINE NOTATION :: T56 BOJ C2 DVR DQ CI EI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 24,431,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 24,431,1973

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - body temperature increase

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,1388,1965

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
6-Bromo-3-(2-chloroethyl)-1H-indole
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
2-(3-Amino-1H-indazol-5-yl)-3-pyridinecarbonitrile
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
(S)-(2,3-Dihydrobenzofuran-3-YL)methanol
Methyl (4-fluorobenzyl)alaninate