[DGlp1,DPhe2,DTrp3,6]-LH-RH

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Names

[ Name ]:
[DGlp1,DPhe2,DTrp3,6]-LH-RH

[Synonym ]:
D-pglu1,D-phe2,D-trp3,6-luteinizing*hormone relea
pglu(1)-phe(2)-trp(3,6)-lhr
LHRH,pGlu(1)-Phe(2)-Trp(3,6)
[D-PGLU1,D-PHE2,D-TRP3,6]-LH-RH
[D-PYR1,D-PHE2,D-TRP3,6]-LH-RH (HUMAN)
(D-PYR1,D-PHE2,D-TRP3,6)-LHRH
DGLP-DPHE-DTRP-SER-TYR-DTRP-LEU-ARG-PRO-GLY-NH2
[D-PYROGLU1,D-PHE2,D-TRP3,6]-LH-RH
(D-Pyr1,D-Phe2,D-Trp3

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₇H₈₄N₁₆O₁₃

[ Molecular Weight ]:
1321.48000

[ Exact Mass ]:
1320.64000

[ PSA ]:
459.24000

[ LogP ]:
4.47690

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R60

[ Safety Phrases ]:
53-22-36/37/39-45

[ RIDADR ]:
NONH for all modes of transport

Articles

Characterization of Leydig cell gonadotropin-releasing hormone binding sites utilizing radiolabeled agonist and antagonist.

Peptides 3(5) , 789-92, (1982)

Gonadotropin-releasing hormone (GnRH) binding sites in intact Leydig cells and in membrane preparations were investigated using 125I-labeled GnRH agonist and antagonist. Binding was saturable and invo...

Role of lipids in gonadotropin releasing hormone agonists and antagonist binding to rat pituitary.

Biochem. Biophys. Res. Commun. 105(1) , 8-13, (1982)

Digestion of pituitary membranes with phospholipase A 2 and phospholipase C abolished, in a dose responsive manner, the specific binding of gonadotropin releasing hormone agonist and antagonist. These...

LH-RH analogue acts as substance P antagonist by inhibiting spinal cord vasomotor responses.

Brain Res. 337(2) , 357-61, (1985)

Intrathecal injections of the luteinizing hormone-releasing hormone (LH-RH) analogue, [D-pGlu1-D-Phe2-D-Trp3,6]-LH-RH caused dose-dependent decreases in mean arterial blood pressure in anesthetized ra...