Glaziovine (VAN) (8CI)

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Names

[ CAS No. ]:
6808-72-6

[ Name ]:
Glaziovine (VAN) (8CI)

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
470.8ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₉NO₃

[ Molecular Weight ]:
297.34800

[ Flash Point ]:
238.5ºC

[ Exact Mass ]:
297.13600

[ PSA ]:
49.77000

[ LogP ]:
2.20430

[ Index of Refraction ]:
1.668

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ2830000

CHEMICAL NAME :: Glaziovine

CAS REGISTRY NUMBER :: 6808-72-6

LAST UPDATED :: 199012

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C18-H19-N-O3

MOLECULAR WEIGHT :: 297.38

WISWESSER LINE NOTATION :: T566 1A L CX FNTT&J F1 KO1 LQ C-& DL6V DXJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,621,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,621,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,621,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 530 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2119,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 190 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,621,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 81 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CTCEA9 Current Therapeutic Research, Clinical & Experimental. (Therapeutic Research Press, Inc., POB 514, Tenafly, NJ 07670) V.1- 1959- Volume(issue)/page/year: 16,621,1974

Related Compounds

1,3,7-Trimethyluric acid
Furo(3,4-b)furan-2,6(3H,4H)-dione, dihydro-3-methylene-4-octyl- (VAN) (8CI)
(2E)-2-[[4-[4-[(2E)-2-(1-anilino-1,3-dioxobutan-2-ylidene)hydrazinyl]-3-chlorophenyl]-2-chlorophenyl]hydrazinylidene]-3-oxo-N-phenylbutanamide
2-phenoxypropionic acid
Turanose
Flavone
4-(2-Cyclopropylethoxy)cyclohexane-1-carboxylic acid
4-(3,4-Dimethoxyphenethoxy)aniline
6-(5-amino-2-methylphenyl)-2-methyl-4-(tetrahydro-2H-pyran-4-yl)pyridazin-3(2H)-one
4-(6-chloro-3-((tetrahydro-2H-pyran-4-yl)oxy)pyridazin-4-yl)morpholine
Tert-butyl 3-cyano-3-methanesulfonylazetidine-1-carboxylate
1H-Pyrazole-5-carboxylic acid, 3-amino-4-[4-(1,1-dimethylethyl)phenyl]-, methyl ester
Tert-butyl 2-cyano-2-(5-methylpyridazin-3-yl)acetate
5-bromo-N-methyl-3-morpholinopicolinamide
4-(5-amino-2-methylphenyl)-N,N-dimethyl-6-morpholinopyrimidin-2-amine
4-(6-Chloroimidazo[1,2-b]pyridazin-8-yl)morpholine-2-carboxylic acid

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