Teprenone

Suppliers

Names

[ CAS No. ]:
6809-52-5

[ Name ]:
Teprenone

[Synonym ]:
5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (E,E,E)-
Geranylgeranyl acetone
GGA
5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-, (5E,9E,13E)-
geranylgeranylacetone
6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
Teprenone
(5E,9E,13E)-6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one
(5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
E36U31
MFCD00866901
Selbex

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
442.2±24.0 °C at 760 mmHg

[ Molecular Formula ]:
C23H38O

[ Molecular Weight ]:
330.55

[ Flash Point ]:
168.0±9.8 °C

[ PSA ]:
17.07000

[ LogP ]:
8.20

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.483

[ Storage condition ]:
?20°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RA5391300
CHEMICAL NAME :
5,9,13,17-Nonadecatetraen-2-one, 6,10,14,18-tetramethyl-
CAS REGISTRY NUMBER :
6809-52-5
LAST UPDATED :
199110
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C23-H38-O
MOLECULAR WEIGHT :
330.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>15 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 16,357,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,703,1990

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
RA5391300

[ HS Code ]:
2914190090

Synthetic Route

Precursor & DownStream

Precursor

  • (4E,8E,12E)-ethyl 2-acetyl-5,9,13,17-tetramethyloctadeca-4,8,12,16-tetraenoate
  • (6E,10E)-3,7,11,15-tetramethylhexadeca-1,6,10,14-tetraen-3-yl 3-oxobutanoate
  • tert-Butyl acetoacetate
  • Geranyllinalool
  • 5-Acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione
  • diazomethane
  • 3,5-dibromo-4-(di-tert-butyl(nonaprenyloxy)silyloxy)benzoic acid
  • Methyl acetoacetate
  • (2E,6E)-Farnesol

DownStream

  • Menaquinone 5

Customs

[ HS Code ]: 2914190090

[ Summary ]:
2914190090 other acyclic ketones without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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Related Compounds

  • Teprenone
  • 7,7-Diethyl-9-(propan-2-yl)-6-oxa-8-azaspiro[3.5]nonane
  • 14-(Propan-2-yl)-6,9-dioxa-13-azadispiro[3.2.5^{7}.2^{4}]tetradecane
  • 9-(Propan-2-yl)-6-oxa-8-azaspiro[3.5]nonane-7-carboxylic acid
  • (2R)-2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4,4-dimethylpentanamido}-3-methylbutanoic acid
  • ethyl 3-(4-tert-butyl-1H-1,2,3-triazol-1-yl)-2,2-difluoropropanoate
  • ethyl 2,2-difluoro-3-[4-(5-hydroxypentyl)-1H-1,2,3-triazol-1-yl]propanoate
  • 5-[2-(1H-indol-3-yl)ethyl]-1,2-oxazol-3-amine
  • ethyl 3-[4-(2-bromoethyl)-1H-1,2,3-triazol-1-yl]-2,2-difluoropropanoate
  • 1-(octahydro-1H-indol-3a-yl)-N-(propan-2-yl)methanesulfonamide
  • N-cyclopropyl-1-(octahydro-1H-indol-3a-yl)methanesulfonamide
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