3,5-dimethyl-2-(piperidin-1-ylmethyl)phenol

Names

[ CAS No. ]:
68097-90-5

[ Name ]:
3,5-dimethyl-2-(piperidin-1-ylmethyl)phenol

[Synonym ]:
3,5-Dimethyl-2-piperidinomethyl-phenol
Ro 3-0590
3,5-dimethyl-2-piperidin-1-ylmethyl-phenol

Chemical & Physical Properties

[ Density]:
1.06g/cm3

[ Boiling Point ]:
333.9ºC at 760 mmHg

[ Molecular Formula ]:
C14H21NO

[ Molecular Weight ]:
219.32300

[ Flash Point ]:
150.5ºC

[ Exact Mass ]:
219.16200

[ PSA ]:
23.47000

[ LogP ]:
2.93280

[ Index of Refraction ]:
1.564

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SL2240000
CHEMICAL NAME :
Phenol, 3,5-dimethyl-2-(piperidinomethyl)-
CAS REGISTRY NUMBER :
68097-90-5
BEILSTEIN REFERENCE NO. :
0165261
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H21-N-O
MOLECULAR WEIGHT :
219.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
69 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 12,194,1957

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Piperidine
  • Formaldehyde
  • 3,5-Dimethylphenol
  • Ethanol

DownStream

  • 2,3,5-Trimethylphenol

Related Compounds

  • 3,6-dimethyl-2-(piperidin-1-ylmethyl)phenol
  • 6-(N-piperidinylmethyl)-2,5-dimethylphenol
  • 2-(7'-chloroquinolin-4'-ylamino)-4,6-bis(3'',5''-dimethylpiperidin-1''-ylmethyl)phenol
  • 1-(3,5-dimethyl-2-piperidin-1-yl-2,3-dihydrofuran-4-yl)ethanone
  • 3-(5-bromo-2-piperidin-1-ylmethyl-phenoxy)-pyridine
  • 3,5-DIMETHYL-4'-PIPERIDINOMETHYL BENZOPHENONE