Methylthiophosphonic acid O,O-dimethyl ester

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Names

[ CAS No. ]:
681-06-1

[ Name ]:
Methylthiophosphonic acid O,O-dimethyl ester

[Synonym ]:
Methyl-thiophosphonsaeure-O,O'-dimethylester
O,O-Dimethyl methylphosphonothioate
methyl-phosphonothioic acid O,O'-dimethyl ester
Phosphonothioic acid,methyl-,O,O-dimethyl ester
dimethoxy-methyl-sulfanylidene-phosphorane
Methan-thiophosphonsaeure-O,O'-dimethylester
methyl thiophosphonate de methyle
methyl-thiophosphonic acid O,O'-dimethyl ester
dimethoxy-methyl-sulfanylidene
Dimethyl methylphosphonothionate
O,O-Dimethyl methanephosphonothioate

Chemical & Physical Properties

[ Density]:
1.141g/cm3

[ Boiling Point ]:
125.8ºC at 760 mmHg

[ Molecular Formula ]:
C3H9O2PS

[ Molecular Weight ]:
140.14100

[ Flash Point ]:
29.9ºC

[ Exact Mass ]:
140.00600

[ PSA ]:
60.36000

[ LogP ]:
1.86910

[ Index of Refraction ]:
1.459

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB1100800
CHEMICAL NAME :
Phosphonothioic acid, methyl-, O,O-dimethyl ester
CAS REGISTRY NUMBER :
681-06-1
LAST UPDATED :
199706
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C3-H9-O2-P-S
MOLECULAR WEIGHT :
140.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>300 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Kidney, Ureter, Bladder - urine volume increased Blood - other changes
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 8,619,1981

Synthetic Route

Precursor & DownStream

Precursor

  • Methanol
  • methylphosphonothioic dichloride
  • Sodium Methylate

DownStream

  • 3-methylidenecyclohexene
  • 1-Methylene-4β-tert-butylcyclohexane

Related Compounds

  • Phosphonothioic acid, O, O- dimethyl ester
  • N-Methylamidothiophosphoric acid O,O-dimethyl ester
  • N-Cyclohexylphosphoramidothioic acid O,O-dimethyl ester
  • methylacetophos
  • 2-dimethoxyphosphinothioylsulfanylacetamide
  • 2-Butenebis(thioic)acid, O,O-dimethyl ester, (E)- (9CI)