Akt Inhibitor IV

Suppliers

Names

[ CAS No. ]:
681281-88-9

[ Name ]:
Akt Inhibitor IV

[Synonym ]:
5-(2-benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1h-benzimidazolium iodide
akt inhibitor iv

Chemical & Physical Properties

[ Molecular Formula ]:
C31H27IN4S

[ Molecular Weight ]:
614.54

[ Exact Mass ]:
614.10000

[ PSA ]:
53.18000

[ LogP ]:
8.31990

MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • Ethyl iodide
  • (4-benzothiazol-2-yl-2-nitrophenyl)phenylamine
  • E-3-(methyl Phenyl Amino)-2-Propenal
  • 2-Aminothiophenol
  • N-Methylaniline
  • 4-Chloro-3-nitrobenzaldehyde

DownStream

Articles

Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia.

J. Thorac. Cardiovasc. Surg. 286 , 9393-404, (2011)

Hypoxia promotes neural stem cell proliferation, the mechanism of which is poorly understood. Here, we have identified the nuclear orphan receptor TLX as a mediator for proliferation and pluripotency ...

Akt signaling pathway: a target for radiosensitizing human malignant glioma.

Neuro. Oncol. 12 , 434-43, (2010)

Radiation therapy plays a central role in the treatment of glioblastoma, but it is not curative due to the high tumor radioresistance. Phosphatidyl-inositol 3-kinase/protein kinase B (Akt) and Janus k...


More Articles


Related Compounds

  • AKT inhibitor IV
  • AKT inhibitor VIII
  • Akt Inhibitor X
  • PTP Inhibitor IV
  • JAK2 Inhibitor IV
  • cFMS Receptor Inhibitor IV
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • 4-((3,5-Dichlorophenyl)amino)-2-((2-(2-hydroxyethoxy)ethyl)amino)-4-oxobutanoic acid