N-[4-(AMINOSULFONYL)-2-CHLOROPHENYL!ACETAMIDE+

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Names

[ Name ]:
N-[4-(AMINOSULFONYL)-2-CHLOROPHENYL!ACETAMIDE+

[Synonym ]:
Acetamide,N-(4-(aminosulfonyl)-2-chlorophenyl)
N-(4-(Aminosulfonyl)-2-chlorophenyl)acetamide
4-acetamido-3-chlorobenzenesulfonamide
PB 310

Chemical & Physical Properties

[ Density]:
1.521g/cm3

[ Molecular Formula ]:
C₈H₉ClN₂O₃S

[ Molecular Weight ]:
248.68700

[ Exact Mass ]:
248.00200

[ PSA ]:
101.13000

[ LogP ]:
3.37640

[ Index of Refraction ]:
1.615

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB4415000

CHEMICAL NAME :: Acetamide, N-(4-(aminosulfonyl)-2-chlorophenyl)-

CAS REGISTRY NUMBER :: 68252-72-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H9-Cl-N2-O3-S

MOLECULAR WEIGHT :: 248.70

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1331,1978

Synthetic Route

Click to get detail synthetic route

Related Compounds

N-[4-(Aminosulfonyl)-2,1,3-benzoxadiazol-7-yl]-2-aminoethyl Methanethiosulfonate
N-[4-(aminosulfonyl)-2-chlorophenyl]-2-(3-phenoxyphenoxy)propanamide
ACETAMIDE, N-[4-(AMINOSULFONYL)-2-METHYLPHENYL]-
ACETAMIDE, N-[4-(AMINOSULFONYL)-2-ETHYLPHENYL]-
N-(2-chloro-4-sulfamoylphenyl)-2,2,2-trifluoroacetamide
N-(2-fluoro-4-sulfamoylphenyl)acetamide
3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(2,2,3,3,3-pentafluoropropyl)carbamoyl]propanoic acid
4-{[1-(3,3-difluorocyclobutyl)ethyl]carbamoyl}-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoic acid
rac-2-({1-[(1R,3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]-N-methylformamido}oxy)acetic acid
2-{[3-cyclopentyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylpropanamido]oxy}acetic acid
2-({1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohex-3-en-1-yl]-N-methylformamido}oxy)acetic acid
rac-2-({1-[(1R,5S)-5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohex-3-en-1-yl]-N-methylformamido}oxy)acetic acid
2-[(1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}-N-methylformamido)oxy]acetic acid
2-({1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-3-yl]-N-methylformamido}oxy)acetic acid
2-({1-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-3-yl]-N-methylformamido}oxy)acetic acid
(1R)-1-(3,5-dimethoxypyridin-4-yl)ethan-1-ol

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