N-Cyclohexyl-2-pyrrolidone

Names

[ Name ]:
N-Cyclohexyl-2-pyrrolidone

[Synonym ]:
N-Cyclohexyl-2-pyrrolidone
MFCD00003191
1-cyclohexylpyrrolidin-2-one
EINECS 229-919-7
2-Pyrrolidinone, 1-cyclohexyl-
1-Cyclohexyl-2-pyrrolidinone

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
304.1±0.0 °C at 760 mmHg

[ Melting Point ]:
12 °C

[ Molecular Formula ]:
C₁₀H₁₇NO

[ Molecular Weight ]:
167.248

[ Flash Point ]:
123.8±9.3 °C

[ Exact Mass ]:
167.131012

[ PSA ]:
20.31000

[ LogP ]:
1.66

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Water Solubility ]:
Soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UY5748450

CHEMICAL NAME :: 2-Pyrrolidinone, 1-cyclohexyl-

CAS REGISTRY NUMBER :: 6837-24-7

BEILSTEIN REFERENCE NO. :: 0121832

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H17-N-O

MOLECULAR WEIGHT :: 167.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,475,1988

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 120 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,587,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 657 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,587,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,587,1984

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H312-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T+:Verytoxic;

[ Risk Phrases ]:
R21/22;R26;R36/37/38

[ Safety Phrases ]:
S23-S24/25-S45-S38-S36/37/39-S28A-S26

[ RIDADR ]:
UN 2810 6.1/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
UY5748450

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29337900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

gamma-Butyrolactone
2-Pyrrolidinone
cyclohexane
Allylcyclohexylamine
carbon monoxide
cyclopropanecarboxylic acid cyclohexylamide
Cyclohexylamine
Bromocyclohexane

DownStream

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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J. Forensic Sci. 52 , 649-655, (2007)

A new method for enhancement of ninhydrin or 1,8-diazafluoren-9-one (DFO)-treated latent fingerprints on thermal paper will be described. Most thermosensitive surfaces of thermal paper become dark whe...

Extraction of aromatics from petroleum naphtha reformate by a 1-cyclohexyl-2-pyrrolidone/ethylene carbonate mixed solvent. Radwan GM, et al.

Ind. Eng. Chem. Res. 36(2) , 414-8, (1997)

PVK/MWNT electrodeposited conjugated polymer network nanocomposite films.

ACS Appl. Mater. Interfaces 3(7) , 2300-8, (2011)

The facile preparation of poly (N-vinyl carbazole) (PVK) and multiwalled carbon nanotubes (MWNTs) solution and conjugated polymer network (CPN) nanocomposite film is described. The stable solutions of...

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