Sulbactam

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Names

[ CAS No. ]:
68373-14-8

[ Name ]:
Sulbactam

[Synonym ]:
penicillanic acid S,S-dioxide
6,6-dihydropenicillanic acid S,S-dioxide
EINECS 269-878-2
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)-
4,4-dioxopenicillanic acid
(2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-Dioxide
penicillanic Acid 1,1-Dioxide
DSSTox_CID_3605
UNII-S4TF6I2330
Sulbactam free acid
(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ<sup>6</sup>-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S,5R)-
Penicillanic Acid Sulfone
Unacim
(2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
Sulbactamum
Sulbactam
acide (2S,5R)-3,3-diméthyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique-4,4-dioxyde

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
567.7±50.0 °C at 760 mmHg

[ Melting Point ]:
146-151ºC

[ Molecular Formula ]:
C8H11NO5S

[ Molecular Weight ]:
233.242

[ Flash Point ]:
297.1±30.1 °C

[ Exact Mass ]:
233.035797

[ PSA ]:
100.13000

[ LogP ]:
-1.39

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.605

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Precautionary Statements ]:
P301 + P312 + P330

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2941109900

Precursor & DownStream

Precursor

  • (3S)-6,6-DIBROMO-2,2-DIMETHYLPENAM-3-CARBOXYLIC ACID 1,1-DIOXIDE
  • Manganese
  • 6-bromo-1,1-dioxopenicillanic acid
  • Nickel
  • (2S,5R)-Benzyl 3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-Dioxide
  • 6-chloro-6-iodopenicillanic acid 1,1-dioxide
  • Tributyltin hydride
  • 6-bromo-6-iodopenicillanic acid 1,1-dioxide
  • (2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 6-Aminopenicillanic acid

DownStream

  • Sulbactam pivoxil
  • Sulbactam sodium

Customs

[ HS Code ]: 2941109900

Articles

Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii.

Antimicrob. Agents Chemother. 59(3) , 1680-9, (2015)

Sulbactam is a class A β-lactamase inhibitor with intrinsic whole-cell activity against certain bacterial species, including Acinetobacter baumannii. The clinical use of sulbactam for A. baumannii inf...

The spread of bla OXA-48 and bla OXA-244 carbapenemase genes among Klebsiella pneumoniae, Proteus mirabilis and Enterobacter spp. isolated in Moscow, Russia.

Ann. Clin. Microbiol. Antimicrob. 14 , 46, (2015)

The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a great problem of healthcare worldwide. Study of the spread for bla OXA-48-like genes coding epidemically significant carbapenemases ...

Investigation of a possible outbreak of carbapenem-resistant Acinetobacter baumannii in Odense, Denmark using PFGE, MLST and whole-genome-based SNPs.

J. Antimicrob. Chemother. 70 , 1965-8, (2015)

The objectives were to study a possible outbreak of carbapenem-resistant Acinetobacter baumannii by comparing three different typing methods (PFGE, MLST and whole-genome SNPs) and to compare the resis...


More Articles

Related Compounds

  • Sulbactam
  • Pivsulbactam
  • SulbactaM M-1
  • Sulbactam sodium
  • Sulbactam-d2 sodium
  • Sulbactam-d5 sodium
  • CID 11074091
  • N-(2,3-Dihydro-1H-inden-5-yl)propionamide
  • 2-chloro-N-[(3,4-dimethoxyphenyl)methyl]-5-piperidin-1-ylsulfonylbenzamide
  • 3-phenyl-4-phenylsulfanyl-1H-pyridazin-6-one
  • 1-(4-Aminopiperidin-1-yl)-2-(2-fluorophenyl)ethanone
  • N-(2-ethylphenyl)-2-(pyridin-4-yl)quinoline-4-carboxamide
  • 4-(Chloromethyl)-2-(3-fluorophenyl)-1,3-thiazole
  • 6-Methoxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid
  • 3-Amino-N-(cyclopropylmethyl)-4-methylbenzamide
  • 5-Methyl-3-[[5-methyl-4-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]oxolan-2-one
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