lorapride

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Names

[ Name ]:
lorapride

[Synonym ]:
Lorapride
4-Amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzenesulfonamide
EINECS 272-057-1
Lorapridum [INN-Latin]
Benzenesulfonamide,4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy
Loraprida [INN-Spanish]
5-Chloro-N(sup 1)-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide
5-chloro-n1-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxysulfanilamide

Chemical & Physical Properties

[ Density]:
1.28g/cm3

[ Boiling Point ]:
507.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₂₂ClN₃O₃S

[ Molecular Weight ]:
347.86100

[ Flash Point ]:
260.7ºC

[ Exact Mass ]:
347.10700

[ PSA ]:
93.04000

[ LogP ]:
3.68420

[ Index of Refraction ]:
1.563

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA9465480

CHEMICAL NAME :: Benzenesulfonamide, 4-amino-5-chloro-N-((1-ethyl-2-pyrrolidinyl)methyl)-2 -methoxy-

CAS REGISTRY NUMBER :: 68677-06-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H22-Cl-N3-O3-S

MOLECULAR WEIGHT :: 347.90

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4225611

Related Compounds

Methyl 7-(4-(difluoromethoxy)phenyl)-5-ethyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
Methyl 7-(3-bromophenyl)-5-ethyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
7-(4-(difluoromethoxy)phenyl)-5-methyl-N-(o-tolyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
tert-Butyl ((4-acetylpyridin-2-yl)methyl)carbamate
Methyl6-methylthieno[2,3-d]pyrimidine-4-carboxylate
2-Ethoxy-6-iodoquinazolin-4-ol
5-Ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylicacid
tert-Butyl 1-methyloctahydro-6H-pyrrolo[2,3-c]pyridine-6-carboxylate
methyl6-bromo-1H-indazole-7-carboxylate
(2R)-3-Fluoro-2-methyl-azetidine

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