IWP-2

Suppliers

Names

[ Name ]:
IWP-2

[Synonym ]:
N-(6-Methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]acetamide
Acetamide, N-(6-methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-
IWP-2

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
257 °C(dec.)

[ Molecular Formula ]:
C₂₂H₁₈N₄O₂S₃

[ Molecular Weight ]:
466.599

[ Exact Mass ]:
466.059174

[ PSA ]:
156.11000

[ LogP ]:
5.25

[ Index of Refraction ]:
1.787

[ Storage condition ]:
Store at +4°C

[ Water Solubility ]:
DMSO: >5mg/mL

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Ligand-independent canonical Wnt activity in canine mammary tumor cell lines associated with aberrant LEF1 expression.

PLoS ONE 9(6) , e98698, (2014)

Pet dogs very frequently develop spontaneous mammary tumors and have been suggested as a good model organism for breast cancer research. In order to obtain an insight into underlying signaling mechani...

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway.

Proc. Natl. Acad. Sci. U. S. A. 112(1) , 166-71, (2015)

The activation of cochlear progenitor cells is a promising approach for hair cell (HC) regeneration and hearing recovery. The mechanisms underlying the initiation of proliferation of postnatal cochlea...

A switch from canonical to noncanonical Wnt signaling mediates early differentiation of human neural stem cells.

Stem Cells 32(12) , 3196-208, (2014)

Wnt/β-catenin signaling is essential for neurogenesis but less is known about β-catenin-independent Wnt signals. We show here that Wnt/activator protein-1 (AP-1) signaling drives differentiation of hu...

IWP-2-V2
(1,2-dimethylpyrrolidin-2-yl)methanol
N-[2-[3,4,5,6,7,8-Hexahydroazocin-1(2H)-yl]ethyl]phenylethylmalonamidic acid ethyl ester
3-(2-carboxy-5-chlorophenyl)-4-fluorobenzoic acid
Benzaldehyde,2,3,4,5,6-pentachloro-
3-(2-carboxy-5-fluorophenyl)-4-fluorobenzoic acid