Amodiaquine dihydrochloride

Suppliers

Names

[ CAS No. ]:
69-44-3

[ Name ]:
Amodiaquine dihydrochloride

[Synonym ]:
Phenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-, hydrochloride (1:1)
TCMDC-123932
camoquinhydrochloride
EINECS 200-706-0
4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol hydrochloride (1:1)
Camoquin Hcl
AMODIAQUIN DIHYDROCHLORIDE
AMODIAQUINE HCL
AMODIAQUIN HYDROCHLORIDE
AMODIAQUINE DIHYDROCHLORIDE
4-[(7-Chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol hydrochloride (1:1)
AMODIAQUINE HYDROCHLORIDE

Chemical & Physical Properties

[ Boiling Point ]:
478ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₃Cl₂N₃O

[ Molecular Weight ]:
392.322

[ Exact Mass ]:
391.121826

[ PSA ]:
48.39000

[ LogP ]:
6.05420

[ Storage condition ]:
-20℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GO7300100

CHEMICAL NAME :: o-Cresol, 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-, dihydrochloride

CAS REGISTRY NUMBER :: 69-44-3

LAST UPDATED :: 199707

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H22-Cl-N3-O.2Cl-H

MOLECULAR WEIGHT :: 428.82

WISWESSER LINE NOTATION :: T66 BNJ IG EMR DQ C1N2&2 &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 52 mg/kg/13W-I

TOXIC EFFECTS :: Blood - agranulocytosis

REFERENCE :: BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 292,717,1986

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 137 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,1471,1981

Safety Information

[ Hazard Codes ]:
N

[ HS Code ]:
2933499090

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%