3,3-Dimethyloxetane

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Names

[ CAS No. ]:
6921-35-3

[ Name ]:
3,3-Dimethyloxetane

[Synonym ]:
3,3-dimethyloxetane
MFCD00005168

Chemical & Physical Properties

[ Density]:
0.835

[ Boiling Point ]:
81ºC

[ Molecular Formula ]:
C5H10O

[ Molecular Weight ]:
86.13230

[ Flash Point ]:
-9ºC

[ Exact Mass ]:
86.07320

[ PSA ]:
9.23000

[ LogP ]:
1.04280

[ Index of Refraction ]:
1.399

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ3150000
CHEMICAL NAME :
Propane, 1,3-epoxy-2,2-dimethyl-
CAS REGISTRY NUMBER :
6921-35-3
BEILSTEIN REFERENCE NO. :
0102430
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C5-H10-O
MOLECULAR WEIGHT :
86.15
WISWESSER LINE NOTATION :
T4OTJ C1 C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,355,1959 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1020 mg/kg/61W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 17,100,1963 *** REVIEWS *** TOXICOLOGY REVIEW 22HAAD "Microbial Toxins, 1970-72," Ajil, S.J., et al., eds., New York, Academic Press, Inc., 1970-72 Volume(issue)/page/year: 6,409,1971

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312 + H332

[ Precautionary Statements ]:
P210-P280

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn;F

[ Risk Phrases ]:
R11;R20/21/22

[ Safety Phrases ]:
16-36/37/39-45

[ RIDADR ]:
UN 1993

[ RTECS ]:
TZ3150000

[ Packaging Group ]:
II

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Bromo-2,2-dimethyl-1-propanol
  • 3-Chloro-2,2-dimethyl-1-propanol
  • Neopentyl glycol
  • Oxetane
  • Carbon dioxide
  • [3-Brom-2.2-dimethyl-propoxy-(1)]-tributyl-zinn
  • 1,3-Dioxan-2-one,5,5-dimethyl-
  • acetic acid (3-bromo-2,2-dimethyl-1-propyl)ester
  • acetic acid,3-chloro-2,2-dimethylpropan-1-ol
  • 2,2-dimethylpropane

DownStream

  • Propane,1,3-dibromo-2,2-dimethyl-
  • 3-Bromo-2,2-dimethyl-1-propanol
  • 2,2-Dimethyl-5-hexen-1-ol
  • 2,3,3-trimethyloxetane
  • 2-Methylbut-2-ene
  • 3-methyl 3-ethyl oxetane
  • 3,3-dimethyloxolane
  • 2-Methylbut-2-ene
  • Allene

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Cyclic oligomers in the cationic polymerization of 3, 3-dimethyloxetane. Bucquoye M and Goethals EJ.

Makromol. Chem. 179(7) , 1681-88, (1978)

Copolymerization of oxetane with 3, 3-dimethyloxetane-I. Reactivity parameters and microstructure of the copolymers. Bucquoye M and Goethals EJ.

Eur. Polymer J. 14(5) , 323-28, (1978)

Mild one-step synthesis of dibromo compounds from cyclic ethers.

J. Org. Chem. 77(24) , 11227-31, (2012)

A novel one-step method for mildly converting cyclic ethers into dibromo compounds is reported. Alcohols, oximes, aldehydes, and ketones are known to react under Appel or Corey-Fuchs reaction conditio...


More Articles

Related Compounds

  • 2-isopropyl-3,3-dimethyloxetane
  • 2-(4-chlorophenyl)-3,3-dimethyloxetane
  • 2-(3-chlorophenyl)-3,3-dimethyloxetane
  • 2-(2-Ethoxyphenyl)-3,3-dimethyloxetane
  • 2,2-bis(4-ethoxyphenyl)-3,3-dimethyloxetane
  • 2,2-bis(4-chlorophenyl)-3,3-dimethyloxetane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-(2-Methoxy-1,3-thiazol-4-yl)-2-methylpropanoic acid
  • 3-((Pyrrolidin-3-ylmethyl)amino)benzo[d]isothiazole 1,1-dioxide hydrochloride
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine