2'-Hydroxy-4'-methylacetophenone

Names

[ CAS No. ]:
6921-64-8

[ Name ]:
2'-Hydroxy-4'-methylacetophenone

[Synonym ]:
EINECS 230-040-6
1-(2-hydroxy-4-methylphenyl)ethanone
MFCD00100559
2'-Hydroxy-4'-methylacetophenone

Chemical & Physical Properties

[ Density]:
1.08 g/mL at 25 °C(lit.)

[ Boiling Point ]:
245 °C(lit.)

[ Melting Point ]:
45-48ºC

[ Molecular Formula ]:
C₉H₁₀O₂

[ Molecular Weight ]:
150.17400

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
150.06800

[ PSA ]:
37.30000

[ LogP ]:
1.90320

[ Index of Refraction ]:
n20/D 1.565(lit.)

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Acaricidal toxicity of 2'-hydroxy-4'-methylacetophenone isolated from Angelicae koreana roots and structure-activity relationships of its derivatives.

J. Agric. Food Chem. 60(14) , 3606-11, (2012)

The acaricidal activities of 2'-hydroxy-4'-methylacetophenone derived from Angelica koreana roots and its derivatives against Dermatophagoides farinae, Dermatophagoides pteronyssinus, and Tyrophagus p...

Zirconium tetrachloride as a mediator for ambient temperature ortho-fries rearrangements. Harrowven DC and Dainty RF.

Tetrahedron 37(42) , 7659-7660, (1996)

4'-Hydroxy-3-methoxyflavones with potent antipicornavirus activity. De Meyer N, et al.

J. Med. Chem. 34(2) , 736-746, (1991)

2'-Hydroxy-4'-methylacetophenone oxime
5'-chloro-2'-hydroxy-4'-methylacetophenone
2'-Hydroxy-4'-methyl-5'-acetylacetophenone
2'-hydroxy-4'-methoxy-4-nitrochalcone
2'-hydroxy-4'-benzyloxy-6'methoxychalkone
2'-hydroxy-4'-iodo-4-benzyloxy-3,5-dimethoxy-chalcone
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine