Naphtho[2,1-b]furan,2-nitro-

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Names

[ CAS No. ]:
69267-51-2

[ Name ]:
Naphtho[2,1-b]furan,2-nitro-

[Synonym ]:
nitro-2 naphto<2,1-b>furanne
nitro-2 naphtol<2,1-b>furanne
nitro-2 naphto<2,1-b>furane
2-nitronaphtho<2,1-b>furan
R6597

Chemical & Physical Properties

[ Density]:
1.399g/cm3

[ Boiling Point ]:
385.2ºC at 760 mmHg

[ Molecular Formula ]:
C12H7NO3

[ Molecular Weight ]:
213.18900

[ Flash Point ]:
186.8ºC

[ Exact Mass ]:
213.04300

[ PSA ]:
58.96000

[ LogP ]:
4.01740

[ Index of Refraction ]:
1.729

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL0842000
CHEMICAL NAME :
Naphtho(2,1-b)furan, 2-nitro-
CAS REGISTRY NUMBER :
69267-51-2
BEILSTEIN REFERENCE NO. :
1376274
LAST UPDATED :
199806
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C12-H7-N-O3
MOLECULAR WEIGHT :
213.20
WISWESSER LINE NOTATION :
T B566 EOJ DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
439 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
443 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
277 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
580 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10489 ug/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
1 umol/L
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 1,217,1986

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2-hydroxynaphthalen-1-yl)methyl-trimethylazanium,iodide
  • potassium,trinitromethane

DownStream

Related Compounds

  • NAPHTHO(2,1-b)FURAN, 1-METHYL-2-NITRO-
  • Naphtho[2,1-b]furan,8-methoxy-2-nitro-
  • Naphtho[2,1-b]furan,7-bromo-2-nitro-
  • Naphtho[2,1-b]furan,4-methoxy-2-nitro-
  • Naphtho[2,1-b]furan-2-methanamine, 1-methyl- (9CI)
  • NAPHTHO[2,1-B]FURAN-2-CARBOHYDRAZIDE
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • N-((1-(cyclopropylsulfonyl)piperidin-4-yl)methyl)-1-methyl-1H-imidazole-4-sulfonamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(3-(5-methylfuran-2-yl)-5-(thiophen-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)ethanone
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-Isopropoxypyrimidin-5-amine
  • L-Seryl-L-prolyl-L-serylglycyl-L-lysyl-L-leucyl-L-methionyl-L-seryl-L-proline
  • (3-((4-Chlorophenyl)sulfonyl)azetidin-1-yl)(pyridin-2-yl)methanone