12-Aminododecanoic acid

Names

[ CAS No. ]:
693-57-2

[ Name ]:
12-Aminododecanoic acid

[Synonym ]:
12-Aminododecanoic acid
Dodecanoic acid, 12-amino-
MFCD00008153
EINECS 211-754-7

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
349.7±15.0 °C at 760 mmHg

[ Melting Point ]:
185-187 °C(lit.)

[ Molecular Formula ]:
C₁₂H₂₅NO₂

[ Molecular Weight ]:
215.33

[ Flash Point ]:
165.3±20.4 °C

[ Exact Mass ]:
215.188522

[ PSA ]:
63.32000

[ LogP ]:
3.08

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.470

[ Storage condition ]:
Store at 0°C

MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

12-nitrododecanoic acid
13-Azacyclotridecan-1-one
Dodecanoic acid, 12-(hydroxyimino)-
11-formylundecanoic acid
(Z)-11-[(2R,3S)-3-pentyloxiran-2-yl]undec-9-enoic acid
7-[5-(acetylamino-methyl)-thiophen-2-yl]-heptanoic acid ethyl ester
1,12-Diaminododecane
methyl 12-aminododecanoate
ethyl 12-aminododecanoate

DownStream

13-Azacyclotridecan-1-one
Boc-12-Ado-OH
12-AMINO-1-DODECANOIC ACID, METHYL ESTER, HYDROCHLORIDE SALT
12-(7-NITROBENZOFURAZAN-4-YLAMINO)DODECANOIC ACID
12-Amino-1-dodecanol
Fmoc-12-Ado-OH
12-[(2,2,2-trifluoroacetyl)amino]dodecanoic acid
12-(t-Boc-amino)-1-dodecanol
AUDA
ethyl 12-aminododecanoate

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.

J. Med. Chem. 48 , 6741-9, (2005)

Improving cellular uptake and biodistribution remains one of the major obstacles for a successful and broad application of peptide nucleic acids (PNAs) as antisense therapeutics. Recently, we reported...

Development of 68Ga-labeled fatty acids for their potential use in cardiac metabolic imaging.

J. Labelled Comp. Radiopharm. 57(7) , 463-9, (2014)

While [(11)C]palmitate continues to be a promising tracer for cardiovascular Positron Emission Tomography (PET) imaging, unfavourable logistics due to the short half-life of (11)C (20 min) and cumbers...

Multi-dye theranostic nanoparticle platform for bioimaging and cancer therapy.

Int. J. Nanomedicine 7 , 2739-50, (2012)

Theranostic nanomaterials composed of fluorescent and photothermal agents can both image and provide a method of disease treatment in clinical oncology. For in vivo use, the near-infrared (NIR) window...