1,2-Diaminocyclohexane

Names

[ CAS No. ]:
694-83-7

[ Name ]:
1,2-Diaminocyclohexane

[Synonym ]:
1,2-Diaminocyclohexane
cyclohexan-1,2-diamin
Cyclohexane-1,2-diamine
EINECS 211-776-7
MFCD00062985

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
193.6±0.0 °C at 760 mmHg

[ Melting Point ]:
41685ºC

[ Molecular Formula ]:
C₆H₁₄N₂

[ Molecular Weight ]:
114.189

[ Flash Point ]:
75.0±0.0 °C

[ Exact Mass ]:
114.115700

[ PSA ]:
52.04000

[ LogP ]:
-0.12

[ Vapour Pressure ]:
0.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.484

[ Water Solubility ]:
miscible

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU8749500

CHEMICAL NAME :: 1,2-Cyclohexanediamine

CAS REGISTRY NUMBER :: 694-83-7

BEILSTEIN REFERENCE NO. :: 0506142

LAST UPDATED :: 199806

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H14-N2

MOLECULAR WEIGHT :: 114.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,8,1990 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4556 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535386

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3200 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 12,357,1992

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3259 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
GU8749500

[ Packaging Group ]:
III

[ Hazard Class ]:
8.0

[ HS Code ]:
29213099

Precursor & DownStream

Precursor

DownStream

tert-Butyl-[(1R,2R)-2-aminocyclohexyl]carbamat
1,2-Cyclohexylenedinitrilotetraacetic acid
1H-BENZIMIDAZOLE, 3A,4,5,6,7,7A-HEXAHYDRO-
N,N'-1,2-cyclohexanediylbis(2-phenoxyacetamide)
HEXAHYDRO-1H-BENZO[D]IMIDAZOLE-2(3H)-THIONE
(1R,2R)-(-)-1,2-Diaminocyclohexane
(1S,2S)-(+)-1,2-Diaminocyclohexane
1,2-Cyclohexanediamine
Adiponitrile
(R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine

Customs

[ HS Code ]: 29213099

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Tendons are dense connective tissues subjected periodically to mechanical stress upon which complex responsive mechanisms are activated. These mechanisms affect not only the development of these tissu...

Steric modifications tune the regioselectivity of the alkane oxidation catalyzed by non-heme iron complexes.

Inorg. Chem. 50(24) , 12651-60, (2011)

Iron complexes with the tetradentate N-donor ligand N,N'-di(phenylmethyl)-N,N'-bis(2-pyridinylmethyl)-1,2-cyclohexanediamine (bbpc) are reported. Despite the benzyl groups present on the amines, the i...

Antitumor platinum(II) complexes of N-monoalkyl-1R, 2R-diaminocyclohexane derivatives with alkyl groups as hindrance.

J. Inorg. Biochem. 112 , 68-76, (2012)

A number of platinum (II) complexes, characteristic of (1R,2R)-N(1)-alkyl-1,2-diaminocyclohexane derivatives as carrier ligands, were designed, synthesized and characterized, where the alkyl group ser...