13-cis-Acitretin

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Names

[ Name ]:
13-cis-Acitretin

[Synonym ]:
Soriatane
9-(4-methoxy-2,3,6-trimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid
9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
(2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
9-(4-Isopropyl-phenyl)-guanin
Neo-Tigasone
Acetretinate
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (all-E)-
(all-E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid
Neotigason
2-amino-9-(4-isopropyl-phenyl)-1,9-dihydro-purin-6-one
Acitretin
2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-, (2E,4E,6E,8E)-
(2E,4E,6E,8E)-3,7-dimethyl-9-[2,3,6-trimethyl-4-(methyloxy)phenyl]nona-2,4,6,8-tetraenoic acid
all-trans-acitretin
SNGP-201-04-E06

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
521.3±38.0 °C at 760 mmHg

[ Melting Point ]:
228-230ºC

[ Molecular Formula ]:
C₂₁H₂₆O₃

[ Molecular Weight ]:
326.429

[ Flash Point ]:
180.3±20.3 °C

[ Exact Mass ]:
326.188202

[ PSA ]:
46.53000

[ LogP ]:
5.73

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.570

[ Storage condition ]:
Amber Vial, -80°C Freezer

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Comparative effectiveness of less commonly used systemic monotherapies and common combination therapies for moderate to severe psoriasis in the clinical setting.

J. Am. Acad. Dermatol. 71(6) , 1167-75, (2014)

The effectiveness of psoriasis therapies in real-world settings remains relatively unknown.We sought to compare the effectiveness of less commonly used systemic therapies and commonly used combination...

Acitretin exhibits inhibitory effects towards UDP-glucuronosyltransferase (UGT)1A9-mediated 4-methylumbelliferone (4-MU) and propofol glucuronidation reaction.

Pharmazie 68(6) , 449-52, (2013)

The present study aimed to evaluate the potential risk of drug-drug interactions associated with acitretin which is a drug for therapy of psoriasis approved by the Food and Drug Administration (FDA). ...

IgA pemphigus: case series with emphasis on therapeutic response.

J. Am. Acad. Dermatol. 70(1) , 200-1, (2014)