5-Brom-3-nitropyridin-2-amin

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Names

[ CAS No. ]:
6945-68-2

[ Name ]:
5-Brom-3-nitropyridin-2-amin

[Synonym ]:
2-Pyridinamine,5-bromo-3-nitro
5-bromo-3-nitro-pyridin-2-ylamine
MFCD00047441
5-Bromo-3-Nitro-2-Pyridinamine
5-Brom-3-nitropyridin-2-amin
5-bromo-3-nitropyridin-2-amine
2-Amino-5-bromo-3-nitropyridine
2-Pyridinamine, 5-bromo-3-nitro-
3-nitro-5-bromopyridin-2-amine
2-Amino-3-nitro-5-bromopyridine

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
302.9±37.0 °C at 760 mmHg

[ Melting Point ]:
205-208 °C(lit.)

[ Molecular Formula ]:
C5H4BrN3O2

[ Molecular Weight ]:
218.01

[ Flash Point ]:
137.0±26.5 °C

[ Exact Mass ]:
216.948685

[ PSA ]:
84.73000

[ LogP ]:
2.79

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.683

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-amino-5-bromopyridine
  • 2-Amino-5-chloropyridine
  • N-(5-bromopyridin-2-yl)nitramide
  • 2-Aminopyridine
  • 3-nitropyridin-2-amin
  • 5-bromo-3-nitropyridine-2-carboxamide
  • Sulfuric acid
  • nitric acid

DownStream

  • 3-Pyridinecarbonitrile,5,6-diamino-(9CI)
  • 5-brompyridin-2,3-diamin
  • 2,5-Dibromo-3-pyridinamine
  • 2,3-Diaminopyridine
  • 2-Amino-3-nitro-5-phenylpyridine
  • 5-Brom-2,3-dichlorpyridin
  • 6-Bromo-4H-imidazo[4,5-b]pyridine
  • 3-Amino-5-bromo-2-hydroxypyridine
  • 3-Amino-5-bromo-2-chloropyridine
  • 5-Bromo-2-chloro-3-nitropyridine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Discovery of 6-({4-[2-(4-tert-butylphenyl)-1H-benzimidazol-4-yl]piperazin-1-yl}methyl)quinoxaline (WAY-207024): an orally active antagonist of the gonadotropin releasing hormone receptor (GnRH-R).

J. Med. Chem. 52(7) , 2148-52, (2009)

A potent, highly insoluble, GnRH antagonist with a 2-phenyl-4-piperazinylbenzimidazole template and a quinoxaline-2,3-dione pharmacophore was modified to maintain GnRH antagonist activity and improve ...

2, 3-Diaminopyridine. Fox BA and Threlfall TL.

Organic Synth. , 34-34, (1973)


More Articles

Related Compounds

  • Ethyl 2-((5-bromo-3-nitropyridin-2-yl)oxy)acetate
  • 5-(3-nitropyridin-2-yl)sulfanyl-3H-1,3,4-thiadiazole-2-thione
  • 5-(3-nitropyridin-2-yl)sulfanyl-1,3,4-thiadiazol-2-amine
  • 6-Methoxy-3-nitropyridin-2-amin
  • 2-Amino-5-nitro-4-picoline
  • [5-bromo-3-(2-carboxy-ethyl)-4-methyl-pyrrol-2-yl]-[5-bromo-3-(2-carboxy-ethyl)-4-methyl-pyrrol-2-ylidene]-methane, hydrobromide
  • methyl (3-(2-phenyl-1H-imidazol-1-yl)propyl)carbamate
  • 2,6-difluoro-N-(3-(2-phenyl-1H-imidazol-1-yl)propyl)benzenesulfonamide
  • N1-(3-(methylthio)phenyl)-N2-(3-(2-phenyl-1H-imidazol-1-yl)propyl)oxalamide
  • 1-(2-fluorophenyl)-3-(3-(2-phenyl-1H-imidazol-1-yl)propyl)urea
  • 1-(3-(2-phenyl-1H-imidazol-1-yl)propyl)-3-(3-phenylpropyl)urea
  • 1-(benzo[d][1,3]dioxol-5-yl)-3-(3-(2-phenyl-1H-imidazol-1-yl)propyl)urea
  • 1-(3-(2-phenyl-1H-imidazol-1-yl)propyl)-3-(3-(trifluoromethyl)phenyl)urea
  • N-(5-oxopyrrolidin-3-yl)-2-phenyl-2H-1,2,3-triazole-4-carboxamide
  • 1-[(4-Chlorophenyl)methyl]-3-(5-oxopyrrolidin-3-yl)urea
  • 2-(cyclopentylthio)-N-(1-methyl-5-oxopyrrolidin-3-yl)acetamide
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