3-Chloromethylpyridinehydrochloride

Suppliers

Names

[ CAS No. ]:
6959-48-4

[ Name ]:
3-Chloromethylpyridinehydrochloride

[Synonym ]:
3-Chloromethylpyridinehydrochloride
3-(Chloromethyl)pyridine hydrochloride (1:1)
EINECS 230-150-4
3-Chloromethylpyridine hydrochloride
Pyridine, 3- (chloromethyl)-, hydrochloride
Pyridine, 3-(chloromethyl)-, hydrochloride (1:1)
3-(chloromethyl)pyridine,hydrochloride
MFCD00012818
3-(Chloromethyl)pyridine, hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
210ºC at 760 mmHg

[ Melting Point ]:
137-143 °C(lit.)

[ Molecular Formula ]:
C6H7Cl2N

[ Molecular Weight ]:
164.033

[ Flash Point ]:
62ºC

[ Exact Mass ]:
162.995560

[ PSA ]:
12.89000

[ LogP ]:
2.62240

[ Water Solubility ]:
>=10 g/100 mL at 19 ºC

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US7000000
CHEMICAL NAME :
Pyridine, 3-chloromethyl-, hydrochloride
CAS REGISTRY NUMBER :
6959-48-4
LAST UPDATED :
199506
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C6-H6-Cl-N.Cl-H
MOLECULAR WEIGHT :
164.04
WISWESSER LINE NOTATION :
T6NJ C1G &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
37 gm/kg/83W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
49 gm/kg/81W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
5 mg/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9,143,1987

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
US7000000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29333999

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Nicotinyl alcohol
  • Nicotinaldehyde

DownStream

  • 1,3-Dihydro-2H-pyrrolo[2,3-b]pyridin-2-on
  • 5,5-bis(pyridin-3-ylmethylsulfanylmethyl)imidazolidine-2,4-dione
  • (6-Chloro-3-pyridinyl)acetonitrile
  • 1-(Pyridin-3-ylmethyl)piperazine
  • 5-Methyl-3-pyridinol
  • 1-((PYRIDIN-3-YL)METHYL)PIPERIDIN-4-ONE
  • Diethyl (3-pyridinylmethyl)phosphonate
  • Nicaraven
  • 3-(Chloromethyl)pyridine
  • 3-((4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOL-1-YL)METHYL)PYRIDINE

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I: Results for nine compounds.

Environ. Mutagen. 9(2) , 143-60, (1987)

Nine substances were tested for their mutagenic potential in the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay, by means of procedures based upon those described by Clive and Spector (Muta...

Assays of three carcinogen/non-carcinogen chemical pairs for in vivo induction of chromosome aberrations, sister chromatid exchanges and micronuclei.

Environ. Mol. Mutagen. 14(4) , 207-20, (1989)

Three pairs of structurally similar carcinogenic/non-carcinogenic chemicals were tested for in vivo genotoxic activity in B6C3F1 mice. The carcinogenic/non-carcinogenic pairs, respectively, were o-tol...


More Articles

Related Compounds

  • 3-benzyl-4-methyl-1,3-thiazol-3-ium,iodide
  • 3-CHLORO-4-(ISOPROPYLSULFONYL)THIOPHENE-2-CARBOXYLIC ACID
  • 3-(1-Benzyl-1H-indol-3-yl)-propionic acid
  • 3,3-diphenyl-4-(2-phenylethenyl)-1-tert-butyl-azetidin-2-one
  • [3-(4-phenylbenzoyl)phenyl]-(4-phenylphenyl)methanone
  • 3-hydroxy-2,2,4-trimethyl-1-(2-methylphenyl)pentan-1-one
  • 3-(Bromomethyl)-2,8-dioxaspiro[4.5]decane
  • 4-[[(3-Fluorophenyl)imino]methyl]phenol
  • Copanlisib-d8
  • 7-Bromo-6-iodo-quinazolin-4-ol
  • methyl 6-methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine-3-carboxylate
  • 1-{1-methyl-1H,2H,3H,4H-pyrrolo[1,2-a]pyrazin-2-yl}prop-2-en-1-one
  • Methyl 2-[cyanomethyl-[2-[3-(2-oxopyrrolidin-1-yl)phenyl]acetyl]amino]acetate
  • (1-Methoxycyclobutyl)methanesulfonamide
  • N-Methyl-N-propan-2-yl-3-prop-2-enoyl-1,3-thiazolidine-4-carboxamide
  • N-(2-Tert-butylpyrimidin-5-yl)prop-2-enamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.