5-Iodouracil

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Names

[ CAS No. ]:
696-07-1

[ Name ]:
5-Iodouracil

[Synonym ]:
5-iodopyriMidine-2.4-diol
EINECS 211-788-2
5IU
2,4(1H,3H)-Pyrimidinedione, 5-iodo-
5-iodopyrimidine-2,4-diol
5-Iodo-2,4(1H,3H)-pyrimidinedione
5-IODOURACIL extrapure
5-iodine uracil
5-iodopyrimidine-2,4(1H,3H)-dione
5-iodo-2,4-dioxopyrimidine
4-iodouracil
5-Iodpyrimidin-2,4(1H,3H)-dion
MFCD00006020
5-Iodouracil
2(1H)-pyrimidinone, 4-hydroxy-5-iodo-
5-iodo-uraci
5-iodo uracil

Chemical & Physical Properties

[ Density]:
2.4±0.1 g/cm3

[ Boiling Point ]:
401ºC

[ Melting Point ]:
274-276 °C (dec.)(lit.)

[ Molecular Formula ]:
C4H3IN2O2

[ Molecular Weight ]:
237.983

[ Exact Mass ]:
237.923904

[ PSA ]:
66.24000

[ LogP ]:
0.14

[ Index of Refraction ]:
1.706

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
SOLUBLE IN COLD WATER

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YR0525000
CHEMICAL NAME :
Uracil, 5-iodo-
CAS REGISTRY NUMBER :
696-07-1
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H3-I-N2-O2
MOLECULAR WEIGHT :
237.99
WISWESSER LINE NOTATION :
T6MVMVJ FI

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 13,1249,1964

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R46;R20/21/22;R36/37/38

[ Safety Phrases ]:
S53-S22-S26-S36/37/39-S45

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
YR0525000

[ HS Code ]:
2933599090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Uracil
  • 1,3-bis(benzyloxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione
  • 5-Aminouracil
  • 2,4-Dimethoxypyrimidine
  • 5-Iodo-2,4-dimethoxypyrimidine
  • 2,4(1H,3H)-Pyrimidinedione,1-acetyl-
  • idoxuridine
  • 1-(chloromethyl)pyrrolidin-2-one
  • 5-iodo-2,4-bis-O-trimethylsilyluracil
  • 5-iodo-6-hydroxylamino-5,6-dihydrouracil

DownStream

  • 5-selenophen-2-yl-1H-pyrimidine-2,4-dione
  • idoxuridine
  • Uracil
  • Thymine
  • 5-vinyluracil
  • 5-iodo-1,3-dimethyluracil
  • Uracil-d1
  • Uracil-d2
  • 5-Iodo-2,4-dimethoxypyrimidine
  • 2,4-Dichloro-5-iodopyrimidine

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Preparation and properties of oligodeoxynucleotides containing 5-iodouracil and 5-bromo- and 5-iodocytosine.

Bioconjug. Chem. 8(5) , 757-61, (1997)

The behavior of oligonucleotides containing 5-iodouracil, 5-bromocytidine, and 5-iodocytidine in concentrated ammonia is described. 5-Aminouracil and 5-aminocytidine are obtained as side products when...


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Related Compounds

  • 5-Iodouracil,TMS
  • N1-benzyl-5-iodouracil
  • N3-benzoyl-5-iodouracil
  • 1,3-dibenzyl-5-iodouracil
  • 5-iodouracil-1-ylacetic acid
  • 1-carboxymethyl-5-iodouracil
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine