(R)-Butaprost

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Names

[ Name ]:
(R)-Butaprost

[Synonym ]:
cyclopentaneheptanoic acid, 3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-buten-1-yl]-5-oxo-, methyl ester, (1R,2R,3R)-
Methyl (11α,13E,16R)-11,16-dihydroxy-9-oxo-17-propyl-17,20-cycloprost-13-en-1-oate
Butaprost
Butaprostum
Methyl (1R,2R,3R)-3-hydroxy-2-((1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)-1-butenyl)-5-oxocyclopentaneheptanoate
Methyl (13E,16R)-11α,16-dihydroxy-9-oxo-17,17-trimethyleneprost-13-en-1-oate
Methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)but-1-en-1-yl]-5-oxocyclopentyl}heptanoate
17,20-Cycloprost-13-en-1-oic acid, 11,16-dihydroxy-9-oxo-17-propyl-, methyl ester, (11α,13E,16R)-
Methyl (13E,16R)-11a,16-Dihydroxy-9-oxo-17,17-trimethyleneprost-13-en-1-oate
Bay q 4218
UNII:HP16WVP23Y
TR-4979
(1R-(1a,2b(1E,4R*),3a))-3-Hydroxy-2-(4-hydroxy-4-(1-propylcyclobutyl)-1-butenyl)-5-oxocyclopentaneheptanoic Acid Methyl Ester

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
525.1±50.0 °C at 760 mmHg

[ Melting Point ]:
-57ºC

[ Molecular Formula ]:
C₂₄H₄₀O₅

[ Molecular Weight ]:
408.571

[ Flash Point ]:
168.4±23.6 °C

[ Exact Mass ]:
408.287567

[ PSA ]:
83.83000

[ LogP ]:
3.51

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.539

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts.

Am. J. Respir. Cell. Mol. Biol. 49(1) , 105-13, (2013)

Numerous epidemiological studies have linked exposure to particulate matter (PM) air pollution with acute respiratory infection and chronic respiratory and cardiovascular diseases. We have previously ...

Resting but not CpG stimulated keratinocytes suppress autologous T-helper cell proliferation--importance of PGE2 and T regulatory function.

Exp. Dermatol. 20(5) , 394-400, (2011)

In the last decade, keratinocytes have increasingly been recognized to actively participate in the skin immune response. However, their influence on infiltrating lymphocytes - abundantly found in e.g....

Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.

Am. J. Physiol. Lung Cell. Mol. Physiol. 298 , L819-29, (2010)

Pulmonary fibroblasts regulate extracellular matrix production and degradation and are critical in maintenance of lung structure, function, and repair, but they also play a central role in lung fibros...

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