D(-)Phenylglycinamide

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Names

[ CAS No. ]:
700-63-0

[ Name ]:
D(-)Phenylglycinamide

[Synonym ]:
(R)-2-Ph-GlyNH2
2-Amino-2-phenylacetamide
EINECS 211-849-3
(R)-(2-phenyl)glycinecarboxamide
Benzeneacetamide, α-amino-
ACETAMIDE,2-AMINO-2-PHENYL
(R-)-(-)-phenylglycine amide
(R)-(-)-2-phenylglycine amide
D(-)Phenylglycinamide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
322.8±35.0 °C at 760 mmHg

[ Melting Point ]:
128-132°C

[ Molecular Formula ]:
C8H10N2O

[ Molecular Weight ]:
150.178

[ Flash Point ]:
149.0±25.9 °C

[ Exact Mass ]:
150.079315

[ PSA ]:
69.11000

[ LogP ]:
-0.11

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.588

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AB4390000
CHEMICAL NAME :
Acetamide, 2-amino-2-phenyl-
CAS REGISTRY NUMBER :
700-63-0
BEILSTEIN REFERENCE NO. :
0972472
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H10-N2-O
MOLECULAR WEIGHT :
150.20
WISWESSER LINE NOTATION :
ZYR&VZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03199

Synthetic Route

Precursor & DownStream

Precursor

  • H-D-Phg-OMe.HCl
  • Nα-[(Benzyloxy)carbonyl]-D-phenylalaninamide
  • methyl (R)-aminophenylacetate
  • 2-amino-2-phenylacetonitrile
  • H-D-Phg-NH2.HCl
  • (R)-phenylglycine nitrile
  • (2-butoxy-2-oxo-1-phenylethyl)azanium,chloride
  • D/L-ALPHA-PHENYLGLYCINEETHYLESTER HYDROCHLORIDE
  • alpha-Phenylglycinonitrile hydrochloride

DownStream

  • H-D-Phg-Leu-OH
  • 2-Phenylpiperazine
  • L-1-Phenylethylamine
  • N-(R)-phenylglycyl-(R)-1-phenylethylamine
  • H-Phg-OH
  • D(-)Phenylglycinamide
  • D(-)Phenylglycinamide
  • D-2-Phenylglycine
  • 5-PHENYLHYDANTOIN
  • Ampicillin

Related Compounds

  • D(-)Phenylglycinamide
  • D(-)Phenylglycinamide
  • D-Nor-5α-androstane-16β-carboxylic acid methyl ester
  • D-Nor-5α-androstan-16β-ol acetate
  • d-menthyl 2-butenoate
  • D-erythro-Sphingosine