(pyrazin-2-ylmethylideneamino)thiourea

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Names

[ CAS No. ]:
7000-48-8

[ Name ]:
(pyrazin-2-ylmethylideneamino)thiourea

[Synonym ]:
2-Pyrazinecarbaldehyde thiosemicarbazone
pyrazine-2-carbaldehyde thiosemicarbazone
Pyrazin-2-carbaldehyd-thiosemicarbazon

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
358.4ºC at 760 mmHg

[ Molecular Formula ]:
C6H7N5S

[ Molecular Weight ]:
181.21800

[ Flash Point ]:
170.5ºC

[ Exact Mass ]:
181.04200

[ PSA ]:
108.28000

[ LogP ]:
0.73490

[ Index of Refraction ]:
1.715

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ2200000
CHEMICAL NAME :
Pyrazinecarboxaldehyde, thiosemicarbazone
CAS REGISTRY NUMBER :
7000-48-8
BEILSTEIN REFERENCE NO. :
0141552
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H7-N5-S
MOLECULAR WEIGHT :
181.24
WISWESSER LINE NOTATION :
T6N DNJ B1UNMYZUS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,585,1966

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-benzenesulfonyl-N'-pyrazinecarbonyl-hydrazine
  • Pyrazinoic acid hydrazide

DownStream

Related Compounds

  • 1,1-dimethyl-3-(pyrazin-2-ylmethylideneamino)thiourea
  • Hydrazinecarbothioamide,N-methyl-2-(2-pyrazinylmethylene)-
  • (quinolin-2-ylmethylideneamino)thiourea
  • (pyridin-2-ylmethylideneamino)thiourea
  • (dipyridin-2-ylmethylideneamino)thiourea
  • 3-methyl-1-(pyridin-2-ylmethylideneamino)thiourea
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • N-methyl-N-(pyridin-2-yl)-[2,2'-bipyridin]-6-amine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide