Tranexamic acid
Suppliers
Names
[ CAS No. ]:
701-54-2
[ Name ]:
Tranexamic acid
[Synonym ]:
1-(biphenyl-4-yl)methanamine
4-aminomethylcyclohexane-1-carboxylic acid
(4-phenylphenyl)methylamine
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-aminomethylbiphenyl
4-Aminomethyl-cyclohexancarbonsaeure
4-Aminomethyl-cyclohexanecarboxylic acid
4-Biphenylmethylamine
4-(Aminomethyl)cyclohexanecarboxylic acid
[1,1'-biphenyl]-4-yl methanamine
C-biphenyl-4-yl-methylamine
4-aminomethylcyclohexane carboxylic acid
4-carboxycyclohexylmethylamine
MFCD00064951
Cyclohexanecarboxylic acid, 4-(aminomethyl)-
(biphenyl-4-ylmethyl)amine
4-Phenylbenzylamine
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
300.2±15.0 °C at 760 mmHg
[ Melting Point ]:
233ºC
[ Molecular Formula ]:
C8H15NO2
[ Molecular Weight ]:
157.210
[ Flash Point ]:
135.4±20.4 °C
[ Exact Mass ]:
157.110275
[ PSA ]:
63.32000
[ LogP ]:
0.31
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.497
[ Storage condition ]:
Refrigerator
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GU8399950
- CHEMICAL NAME :
- Cyclohexanecarboxylic acid, 4-(aminomethyl)-
- CAS REGISTRY NUMBER :
- 701-54-2
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C8-H15-N-O2
- MOLECULAR WEIGHT :
- 157.24
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >15 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >15 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 32500 mg/kg/13W-I
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- REFERENCE :
- APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965
Safety Information
[ RTECS ]:
GU8399950
[ HS Code ]:
2922499990
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%