MEDROXALOL HYDROCHLORIDE

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Names

[ CAS No. ]:
70161-10-3

[ Name ]:
MEDROXALOL HYDROCHLORIDE

[Synonym ]:
Medroxalol HCl
Medroxalol hydrochloride
Medroxalol hydrochloride [USAN]
EINECS 274-347-3
Benzamide,5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-hydroxy-,monohydrochloride
5-(2-((3-(1,3-Benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)salicylamide monohydrochloride
5-[1-hydroxy-2-[4-(3,4-methylenedioxyphenyl)-2-butylamino]ethyl]salicylamide hydrochloride
5-(2-((3-(1,3-Benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-hydroxybenzamide HCl

Chemical & Physical Properties

[ Boiling Point ]:
604.1ºC at 760 mmHg

[ Molecular Formula ]:
C20H24N2O5

[ Molecular Weight ]:
372.41500

[ Flash Point ]:
319.1ºC

[ Exact Mass ]:
372.16900

[ PSA ]:
114.04000

[ LogP ]:
2.95530

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV2347360
CHEMICAL NAME :
Benzamide, 5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino) -1-hydroxyethyl)-2-hy droxy-, monohydrochloride
CAS REGISTRY NUMBER :
70161-10-3
LAST UPDATED :
199507
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H24-N2-O5.Cl-H
MOLECULAR WEIGHT :
408.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
137 gm/kg/78W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Musculoskeletal - tumors
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 15,457,1987

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • Elacridar hydrochloride
  • dodecylamine hydrochloride
  • Azetidine, hydrochloride, homopolymer (9CI)
  • 2-{[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-phenylacetamido]methyl}butanoic acid
  • ethyl 4-[(2S)-2-aminopropyl]piperidine-1-carboxylate
  • 1-({[1-benzyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pyrrolidin-3-yl]formamido}methyl)cyclopentane-1-carboxylic acid
  • 3-[3-(Methoxycarbonyl)phenyl]-3-methylbutanoic acid
  • 3-[benzyl(methyl)amino]-2-({4-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxan-4-yl}formamido)propanoic acid
  • 3-[benzyl(methyl)amino]-2-{[3-chloro-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]formamido}propanoic acid
  • 3-cyclopropyl-4-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanamido]butanoic acid
  • (2,3,4-Trimethoxyphenyl)methanesulfonyl fluoride
  • Arsonic acid, [3-(acetylamino)-4-fluorophenyl]-
  • ethyl({[5-(3-methoxyphenyl)-1H-pyrazol-3-yl]methyl})amine
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