2-Chloro-5-chloromethylpyridine

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Names

[ Name ]:
2-Chloro-5-chloromethylpyridine

[Synonym ]:
2-chloropyridyl-5-methylene chloride
6-Chlo
imidacloprid impurity
2-chloro-5-chloromethyl-pyridine
MFCD00125366
Pyridine, 2-chloro-5-(chloromethyl)-
2-Chlor-5-Chlormethylpyridine
2-Chloro-5-chloromethylpyridine
2-Chloro-5-(chloromethyl)pyridine
2-Chloro-5-pyridylMethyl chloride
2-Chloro-5-Chloro-Me
5-chloromethyl-2-chloropyridine
6-chloro-nicotinyl chloride
AURORA KA-6694
2,5-DICHLORO-4-METHYL-PYRIDINE
2-CHLORO-5-CHLOROMETHYL PYRIDINE (CCMP),60% DMF

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
249.8±25.0 °C at 760 mmHg

[ Melting Point ]:
37-42 °C(lit.)

[ Molecular Formula ]:
C₆H₅Cl₂N

[ Molecular Weight ]:
162.017

[ Flash Point ]:
129.0±8.8 °C

[ Exact Mass ]:
160.979904

[ PSA ]:
12.89000

[ LogP ]:
1.67

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.551

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S25

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8.0

[ HS Code ]:
2933399010

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

5-(Hydroxymethyl)pyridin-2(1H)-one
(6-Chlorpyridin-3-yl)methanol
6-Chloronicotinic acid
Phosphorus pentachloride
(6-Methoxypyridin-3-yl)methanol
N,N-Dibutylformamide
dichloroethane
Carbon
4-chloro-4-chloromethyl-5-oxopentamide

DownStream

2-[[(6-CHLORO-3-PYRIDINYL)METHYL]AMINO]-ETHANOL
2-chloro-5-[[2-(nitromethylidene)pyrrolidin-1-yl]methyl]pyridine
(6-Chloro-3-pyridinyl)acetonitrile
(6-Chloro-3-pyridinyl)acetic acid
[(6-chloropyridin-3-yl)methyl]dimethylamine
2-N,N-dimethylamino-5-[(N,N-dimethylamino)methyl]pyridine
2-chloro-5-(piperidin-1-ylmethyl)pyridine
2-chloro-5-(pyrrolidin-1-ylmethyl)pyridine
4-((6-Chloropyridin-3-yl)methyl)morpholine
(2-chloropyridin-3-yl)methanamine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Novel and potent 6-chloro-3-pyridinyl ligands for the alpha4beta2 neuronal nicotinic acetylcholine receptor.

J. Med. Chem. 42(12) , 2227-34, (1999)

1-[(6-Chloro-3-pyridinyl)methyl]-2-imidazolidine (1), the N-desnitro metabolite of the major insecticide imidacloprid, is known to have similar potency to that of (-)-nicotine as an inhibitor of [3H](...

2-Chloro-5-(chloromethyl) pyridine. Feng ZQ, et al.

Acta Crystallogr. Sect. E Struct. Rep. Online 67(2) , o366-o366, (2011)

2-chloro-5-chloromethylpyridine chydrochloride
2-chloro-5-(chloromethyl)-3-methylpyridine
2-chloro-3-bromo-5-chloromethylpyridine
2-chloro-5-(4-chloro-3-sulfophenyl)sulfonylbenzenesulfonic acid
2-chloro-5-hydroxy-6-methylpyridine-3-carboxylic acid
2-chloro-5-phenylaniline
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(4-fluorobenzyl)oxalamide
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-hydroxyethyl)oxalamide
N1-(4-chlorophenethyl)-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
N1-(benzo[d][1,3]dioxol-5-ylmethyl)-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(thiophen-2-ylmethyl)oxalamide
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(pyridin-2-ylmethyl)oxalamide
N1-cycloheptyl-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
N1-(2-(1H-indol-3-yl)ethyl)-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-phenethyloxalamide
N1-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-fluorobenzyl)oxalamide

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