N-(2-thiazolyl)-3-oxo-butanamide

Names

[ CAS No. ]:
705-87-3

[ Name ]:
N-(2-thiazolyl)-3-oxo-butanamide

[Synonym ]:
2-Acetylacetamino-thiazol
3-oxo-N-thiazol-2-yl-butyramide
2-acetoacetamidothiazole
3-keto-N-thiazol-2-yl-butyramide
N-Thiazol-2-yl-acetoacetamid
2-Acetacetamido-thiazol

Chemical & Physical Properties

[ Density]:
1.361g/cm3

[ Molecular Formula ]:
C7H8N2O2S

[ Molecular Weight ]:
184.21600

[ Exact Mass ]:
184.03100

[ PSA ]:
87.30000

[ LogP ]:
1.13370

[ Index of Refraction ]:
1.599

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AK4100000
CHEMICAL NAME :
Acetoacetamide, N-2-thiazolyl-
CAS REGISTRY NUMBER :
705-87-3
BEILSTEIN REFERENCE NO. :
0149764
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-N2-O2-S
MOLECULAR WEIGHT :
184.23
WISWESSER LINE NOTATION :
T5N CSJ BMV1V1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03629

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Aminothiazole
  • 2,2,6-Trimethyl-4H-1,3-dioxin-4-one
  • Ethyl acetoacetate

DownStream

  • 2-[(4-nitrophenyl)methylidene]-3-oxo-N-(1,3-thiazol-2-yl)butanamide

Related Compounds

  • N-(2-methoxyethyl)-3-oxo-butanamide
  • N-(2,3-dimethylphenyl)-3-oxo-butanamide
  • N-[2-chloro-5-(trifluoromethyl)phenyl]-3-oxo-butanamide
  • N-[2-(3-oxo-2,4-dihydro-1H-isoquinolin-1-yl)phenyl]-2-(propylamino)acetamide
  • N-(2-(3-oxo-3-phenylpropyl)phenyl)benzenesulfonamide
  • Sudoxicam
  • Dioxosilane;trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
  • Disodium;2-(chloromethyl)oxirane;prop-2-yn-1-ol;sulfite
  • Bromomethane;tribromoalumane
  • CID 90659523
  • 1H-indole;2-methyl-3-pentylcyclopent-2-en-1-one
  • Sodium;hydrogen carbonate;2-oxopropanoic acid;propane-1,2-diol
  • 4-Anilinobenzenediazonium;dichlorozinc;formaldehyde;chloride
  • (R)-1-(2-Fluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-amine
  • (3R)-3-Amino-3-(1H-imidazol-4-yl)propan-1-ol
  • (S)-1-(2-Fluorophenyl)-4,5,6,7-tetrahydro-1H-indazol-4-amine
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