1-Chloro-3,5-dimethoxybenzene

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Names

[ CAS No. ]:
7051-16-3

[ Name ]:
1-Chloro-3,5-dimethoxybenzene

[Synonym ]:
Benzene, 1-chloro-3,5-dimethoxy-
MFCD00008382
1-Chloro-3,5-dimethoxybenzene
EINECS 230-330-2

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
239.0±20.0 °C at 760 mmHg

[ Melting Point ]:
34-36 °C(lit.)

[ Molecular Formula ]:
C8H9ClO2

[ Molecular Weight ]:
172.609

[ Flash Point ]:
112.2±0.0 °C

[ Exact Mass ]:
172.029114

[ PSA ]:
18.46000

[ LogP ]:
2.99

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.508

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ0320000
CHEMICAL NAME :
Benzene, 1-chloro-3,5-dimethoxy-
CAS REGISTRY NUMBER :
7051-16-3
BEILSTEIN REFERENCE NO. :
2327304
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H9-Cl-O2
MOLECULAR WEIGHT :
172.62
WISWESSER LINE NOTATION :
GR CO1 EO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01335

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CZ0320000

[ HS Code ]:
2909309090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloro-4,6-dimethoxyaniline
  • 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 4-Chloro-2,6-dimethoxybenzoic acid
  • 3,5-DICHLOROANISOL
  • Sodium Methylate
  • 1,3-Dimethoxybenzene
  • 4-Benzoquinone Monoxime
  • 3-Chloro-5-methoxyphenol
  • Dimethyl sulfate
  • 3,5-Dimethoxyaniline

DownStream

  • 3,5-Dimethoxybenzylamine
  • 5-chlorobenzene-1,3-diol
  • 1,3-Dimethoxy-5-methylbenzene
  • 3,5-Dimethoxyphenol
  • 1,3-Dimethoxybenzene
  • 1,3-dimethoxy-5-(4-methylphenyl)benzene
  • (3,5-DICHLORO-PYRIDIN-4-YL)METHYLAMINE
  • 2-(3,5-Dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 3,5-dimethoxy-N,N-dimethylaniline
  • 2-chloro-4,6-dimethoxybenzaldehyde

Customs

[ HS Code ]: 2909309090

[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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Related Compounds

  • 1-chloro-3,5-bis(trichloromethyl)benzene
  • 1-Chloro-3,5-dinitrobenzene
  • 1-chloro-3-[5-(3-chloro-2-hydroxypropoxy)pentoxy]propan-2-ol
  • 1-chloro-3,5-dimethyl-hex-2-ene
  • 1-chloro-3,5-difluoro-2-(trifluoromethyl)benzene
  • 1-chloro-3,5-difluoro-2-nitrobenzene
  • 3-bromo-7-(difluoromethyl)-2-ethyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyrimidine
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  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
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  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide