CHLORPHENAMINE MALEATES
Suppliers
Names
[ CAS No. ]:
7054-11-7
[ Name ]:
CHLORPHENAMINE MALEATES
[Synonym ]:
chlorphenamine maleate
chloropheniramine maleate
chlortrimeton
Chemical & Physical Properties
[ Melting Point ]:
130-135ºC(lit.)
[ Molecular Formula ]:
C20H23ClN2O4
[ Molecular Weight ]:
390.86100
[ Exact Mass ]:
390.13500
[ PSA ]:
90.73000
[ LogP ]:
3.14170
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US6503000
- CAS REGISTRY NUMBER :
- 7054-11-7
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C16-H19-Cl-N2.C4-H4-O4
- MOLECULAR WEIGHT :
- 390.90
- WISWESSER LINE NOTATION :
- T6NJ BYR DG&2N1&1 &QV1U1VQ -+-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 118 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 89 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 73 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 24,181,1994
Safety Information
[ Hazard Codes ]:
T,Xi
[ Risk Phrases ]:
25-36/37/38
[ Safety Phrases ]:
36/37/39-45-36-26
[ RIDADR ]:
UN 2811 6.1/PG 3