NS 3763

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Names

[ CAS No. ]:
70553-45-6

[ Name ]:
NS 3763

[Synonym ]:
NS3763
5-Carboxy-2,4-dibenzamidobenzoic acid

Chemical & Physical Properties

[ Density]:
1.485g/cm3

[ Boiling Point ]:
490.7ºC at 760 mmHg

[ Molecular Formula ]:
C22H16N2O6

[ Molecular Weight ]:
404.37200

[ Flash Point ]:
250.6ºC

[ Exact Mass ]:
404.10100

[ PSA ]:
132.80000

[ LogP ]:
3.73360

[ Index of Refraction ]:
1.735

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H410

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338-P501

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi,N

[ Risk Phrases ]:
36/37/38-50/53

[ Safety Phrases ]:
26-36-60-61

[ RIDADR ]:
UN 3077 9/PG 3

Articles

Adenine nucleotide translocator cooperates with core cell death machinery to promote apoptosis in Caenorhabditis elegans.

Mol. Cell. Biol. 29 , 3881-93, (2009)

In Caenorhabditis elegans, the central cell-killing process is essentially controlled by the interplay of four apoptotic factors: EGL-1/BH3-only protein, CED-9/Bcl2, CED-4/Apaf1, and CED-3/caspase. In...

Neurotoxic effects of TDP-43 overexpression in C. elegans.

Hum. Mol. Genet. 19 , 3206-18, (2010)

RNA-binding protein TDP-43 has been associated with multiple neurodegenerative diseases, including amyotrophic lateral sclerosis and frontotemporal lobar dementia. We have engineered pan-neuronal expr...

Shared developmental roles and transcriptional control of autophagy and apoptosis in Caenorhabditis elegans.

J. Cell Biol. 124 , 1510-8, (2011)

Autophagy is a lysosome-mediated self-degradation process of eukaryotic cells that, depending on the cellular milieu, can either promote survival or act as an alternative mechanism of programmed cell ...


More Articles


Related Compounds

  • NS 5806
  • NS-1209
  • NS-018 maleate
  • NS 6740
  • NS-1619
  • NS-3-008 hydrochloride
  • 3,6-Bis(3-nitrophenyl)piperazine-2,5-dione
  • 2-(5-chloro-2-methylphenyl)-4-[(3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl]-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 3-benzyl-2-[(cyclopropylmethyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-4-one
  • 2-(3,4-dimethylphenyl)-4-(prop-2-en-1-yl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 2-(3,5-dimethylphenyl)-4-(prop-2-en-1-yl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 2-(5-chloro-2-methylphenyl)-4-[(oxan-4-yl)methyl]-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 4-(cyclobutylmethyl)-2-(3,5-dimethylphenyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 2-(2,5-dimethylphenyl)-4-(2-methylprop-2-en-1-yl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 2-(5-chloro-2-methylphenyl)-4-(cyclopropylmethyl)-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-1,1,3-trione
  • 3-benzyl-2-[(cyclobutylmethyl)sulfanyl]-3H,4H-thieno[3,2-d]pyrimidin-4-one
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