2-Phenylimidazo(2,1-a)isoquinoline

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Names

[ CAS No. ]:
70845-68-0

[ Name ]:
2-Phenylimidazo(2,1-a)isoquinoline

[Synonym ]:
Imidazo(2,1-a)isoquinoline,2-phenyl
2-Phenyl-imidazo<2.1-a>isochinolin
2-Phenylimidazo(2,1-a)isoquinoline

Chemical & Physical Properties

[ Density]:
1.17g/cm3

[ Molecular Formula ]:
C17H12N2

[ Molecular Weight ]:
244.29100

[ Exact Mass ]:
244.10000

[ PSA ]:
17.30000

[ LogP ]:
4.15450

[ Index of Refraction ]:
1.671

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NI3029000
CHEMICAL NAME :
Imidazo(2,1-a)isoquinoline, 2-phenyl-
CAS REGISTRY NUMBER :
70845-68-0
BEILSTEIN REFERENCE NO. :
0015101
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H12-N2
MOLECULAR WEIGHT :
244.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
15 mg/kg
SEX/DURATION :
female 6-10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1222,1983
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
1250 ug/kg
SEX/DURATION :
female 4-8 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1222,1983

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Isoquinoline
  • 2-Bromoacetophenone
  • N-Hydroxybenzenecarboximidoyl chloride
  • 3-Isoquinolinamine
  • Acetophenone
  • (1-phenylethylideneamino) acetate
  • 1-ISOQUINOLINAMINE
  • Phenylacetylene
  • N-(1-phenylethylidene)-N-(4H-1,2,4-triazol-4-yl)amine
  • 2-Phenyl-5,6-dihydroimidazo(2,1-a)isoquinoline

DownStream

  • 2-Phenyl-5,6-dihydroimidazo(2,1-a)isoquinoline

Related Compounds

  • 5,6-Dihydro-2-phenylimidazo(2,1-a)isoquinoline
  • 2-phenylimidazo[2,1-a]phthalazine
  • 2-PHENYL-IMIDAZO[2,1-A]PHTHALAZIN-6-YLAMINE
  • 2-Methylimidazo[2,1-a]isoquinoline
  • 2-fluoropyrrolo[2,1-a]isoquinoline-3-carbonitrile
  • 2-phenylpyrrolo[2,1-a]isoquinoline
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Phenol, 4-[(2R)-2-aminobutoxy]-
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide