1,2,16-trimethoxy-5-oxo-7,8-dihydro-5H-benzo[6,7]azocino[2,1-a][1,3]dioxolo[4,5-g]isoquinoline-14,15-dicarboxylic acid dimethyl ester

Names

[ CAS No. ]:
70866-50-1

[ Name ]:
1,2,16-trimethoxy-5-oxo-7,8-dihydro-5H-benzo[6,7]azocino[2,1-a][1,3]dioxolo[4,5-g]isoquinoline-14,15-dicarboxylic acid dimethyl ester

[Synonym ]:
berberine deriv jci 2222

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
765.7ºC at 760 mmHg

[ Molecular Formula ]:
C27H25NO10

[ Molecular Weight ]:
523.48800

[ Flash Point ]:
416.9ºC

[ Exact Mass ]:
523.14800

[ PSA ]:
119.06000

[ LogP ]:
2.49710

[ Index of Refraction ]:
1.641

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 8,9,10-trimethoxy-13-oxo-5,6,8,13-tetrahydro-8,13a-etheno-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline-15,16-dicarboxylic acid dimethyl ester

DownStream

  • dimethyl 3-(2,3-dimethoxy-6-methoxycarbonylphenyl)-5,6-dihydro-[1,3]benzodioxolo[5,6-g]indolizine-1,2-dicarboxylate
  • dimethyl 3-(3,4-dimethoxy-2-(methoxycarbonyl)phenyl)-5,6-dihydro-[1,3]dioxolo[4,5-g]pyrrolo[2,1-a]isoquinoline-1,2-dicarboxylate
  • 12aH-1,3-Dioxolo[4,5-g]indeno[2',1':4,5]pyrrolo[2,1-a]isoquinoline-12a,13-dicarboxylicacid, 5,6,7a,12-tetrahydro-7a-hydroxy-8,9-dimethoxy-12-oxo-, 12a,13-dimethylester