Suxamethonium chloride
Suppliers
Names
[ CAS No. ]:
71-27-2
[ Name ]:
Suxamethonium chloride
[Synonym ]:
2,2'-[(1,4-Dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride
2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethylethanaminium] Dichloride
2,2'-[(1,4-Dioxo-1,4-butanediyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) dichloride
Succinylcholine Chloride
Succinic Acid Bis[b-dimethylaminoethyl] Ester Dimethochloride
Suxamethonium chloride
QUELICIN
Succinylcholine dichloride
Succinyldicholine chloride
MFCD00038725
succinylcholine chloride (anhydrous)
Succinylcholine Chloride Dihydrate
Listenon
Succinic acid bis[β-dimethylaminoethyl] ester dimethochloride
Ultrapal Chloride
EINECS 200-747-4
Suxamethoniumchloride
Ethanaminium, 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)
Suxamethonium dichloride
Bis[2-dimethylaminoethyl]succinate Bis[methochloride]
Succinyldicholine dichloride
2,2'-[(1,4-Dioxobutan-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium)dichlorid
trimethyl-[2-[4-oxo-4-[2-(trimethylazaniumyl)ethoxy]butanoyl]oxyethyl]azanium,dichloride
Chemical & Physical Properties
[ Melting Point ]:
164ºC
[ Molecular Formula ]:
C14H30Cl2N2O4
[ Molecular Weight ]:
361.305
[ Exact Mass ]:
360.158264
[ PSA ]:
52.60000
[ Storage condition ]:
Refrigerator
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GA2360000
- CAS REGISTRY NUMBER :
- 71-27-2
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C14-H30-N2-O4.2Cl
- MOLECULAR WEIGHT :
- 361.36
- WISWESSER LINE NOTATION :
- 1K1&1&2OV2VO2K1&1&1 &Q 2 &G 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 1429 ug/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - changes in potassium
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human - man
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - changes in potassium Cardiac - arrhythmias (including changes in conduction)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 430 ug/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 240 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - altered sleep time (including change in righting reflex) Behavioral - rigidity (including catalepsy)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 300 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 2500 ug/kg
- REFERENCE :
- MSCREJ Medical Science Research. (Elsevier Applied Science Pub. Ltd., Crown House, Linton Rd., Barking, Essex IG11 8JU, UK) V.15- 1987- Volume(issue)/page/year: 20,759,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84013 No. of Facilities: 25 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 400 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84013 No. of Facilities: 207 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 10334 (estimated) No. of Female Employees: 9106 (estimated)
Safety Information
[ Safety Phrases ]:
7-8
[ RIDADR ]:
UN 3249
[ RTECS ]:
GA2360000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2923900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2923900090
[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%