Cobalt acetate

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Names

[ CAS No. ]:
71-48-7

[ Name ]:
Cobalt acetate

[Synonym ]:
EINECS 200-755-8
MFCD00008689
cobalt(ii) acetate
Cobalt(2+) diacetate
cobalt(2+),diacetate
Acetic acid, cobalt(2+) salt (2:1)
Cobalt diacetate
anhydrous cobalt acetate
Cobalt acetate
Cobaltous diacetate

Chemical & Physical Properties

[ Density]:
1.7043g/cm3

[ Boiling Point ]:
117.1ºC at 760 mmHg

[ Melting Point ]:
298ºC (dec.)

[ Molecular Formula ]:
C2H4CoO2

[ Molecular Weight ]:
177.021

[ Flash Point ]:
40ºC

[ Exact Mass ]:
176.959808

[ PSA ]:
37.30000

[ LogP ]:
0.09090

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AG3150000
CHEMICAL NAME :
Acetic acid, cobalt(2+) salt
CAS REGISTRY NUMBER :
71-48-7
LAST UPDATED :
199710
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C4-H6-O4.Co
MOLECULAR WEIGHT :
177.03
WISWESSER LINE NOTATION :
OV1 2 &-CO-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
503 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
31 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 mg/m3/24H/17W-C
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
135 mg/kg/9D-I
TOXIC EFFECTS :
Cardiac - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases Biochemical - Neurotransmitters or modulators (putative) - catecholamine levels in sympathetic nerves

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,193,1979 *** REVIEWS *** IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,363,1991 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 52,363,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO COBALT METAL, dust and fume-air:10H TWA 0.05 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81777 No. of Facilities: 603 (estimated) No. of Industries: 8 No. of Occupations: 20 No. of Employees: 5023 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81777 No. of Facilities: 622 (estimated) No. of Industries: 13 No. of Occupations: 16 No. of Employees: 15156 (estimated) No. of Female Employees: 4580 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H317-H319-H334-H341-H350i-H360F-H410

[ Precautionary Statements ]:
P201-P261-P280-P284-P304 + P340-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38;R40;R43;R53

[ Safety Phrases ]:
S22-S26-S36/37/39-S45

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
2

[ RTECS ]:
AG3150000

Synthetic Route

Precursor & DownStream

Precursor

  • cobalt acetate tetrahydrate
  • acetic acid
  • Tributylphosphine
  • Ethanoic anhydride
  • Cobalt

DownStream

  • Cobalt protoporphyrin IX
  • 1-acetyl-3-hydroxyadamantane
  • (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(II)
  • DYSPROSIUM ACETATE
  • Cobalt chloride
  • 3-Methyl-1-butanol
  • isobutanol
  • pentanol
  • Butanol
  • 1-Cyclohexylethan-1-one

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Related Compounds

  • cobalt acetate
  • anhydrous cobalt acetate
  • cobalt acetate tetrahydrate
  • Cobalt, acetate borate complexes
  • Cobalt, bis[4-(imino-kN)-2-pentanonato-kO]-
  • cobalt(ii) chloride hydrate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidine-4-carboxylic acid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide