Isopropamide iodide

Suppliers

Names

[ CAS No. ]:
71-81-8

[ Name ]:
Isopropamide iodide

[Synonym ]:
Priazimide
Isopropamide Iodide
Piaccamide
Dipramid
Priamide
Dipramide
Darbid
2,2-diphenyl-4-diisopropylaminobutyramide methiodide
Priamide Eupharma
Sanulcin
Isoproponum iodide

Chemical & Physical Properties

[ Density]:
1.2711 (estimate)

[ Melting Point ]:
199℃ (Decomposition)

[ Molecular Formula ]:
C23H33IN2O

[ Molecular Weight ]:
480.42500

[ Exact Mass ]:
480.16400

[ PSA ]:
43.09000

[ LogP ]:
1.81580

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BP0693200
CHEMICAL NAME :
Ammonium, (3-carbamoyl-3,3-diphenylpropyl)diisopropylmethyl-, iodide
CAS REGISTRY NUMBER :
71-81-8
LAST UPDATED :
199806
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C23-H33-N2-O.I
MOLECULAR WEIGHT :
480.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,1318,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1600 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Sense Organs and Special Senses (Eye) - lacrimation Autonomic Nervous System - parasympatholytic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 103,120,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Sense Organs and Special Senses (Eye) - lacrimation Autonomic Nervous System - parasympatholytic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 103,120,1955
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12779 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 103,100,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4907 No. of Facilities: 200 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 801 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4907 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 690 (estimated) No. of Female Employees: 414 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
BP0693200

[ HS Code ]:
2924299090

Synthetic Route

Precursor & DownStream

Precursor

  • 4-[bis(isopropyl)amino]-2,2-diphenylbutyronitrile
  • Benzeneacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-
  • methyl iodide

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

  • Isopropamide
  • Triphenylmethylphosphinium iodide
  • dioctadecylthiacarbocyanine iodide
  • thymol iodide
  • Heptafluoroisopropyl iodide
  • Pyridium iodide
  • 1-{1H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}cyclopentan-1-amine
  • 2,2-Difluoro-3-(1-phenylcyclopentyl)propan-1-amine
  • 3-[1-(2-Aminoethyl)cyclopropyl]-2,2-dimethyl-1lambda6-thiolane-1,1-dione
  • [2-(2-Fluoro-5-nitrophenyl)cyclopropyl]methanamine
  • 1-(2-Bromo-3-nitrophenyl)cyclopentan-1-amine
  • 1-(1-benzyl-3,5-dimethyl-1H-pyrazol-4-yl)cyclopentan-1-amine
  • 4-(3-amino-2,2-dimethylpropyl)-N,N-diethylaniline
  • 4-methyl-4-(1-methyl-1H-pyrazol-5-yl)pyrrolidin-2-one
  • (2S)-4-(1-methyl-1H-1,2,3-triazol-4-yl)butan-2-amine
  • (1-{[3-(Methylsulfanyl)phenyl]methyl}cyclopropyl)methanamine
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