2-Acetyl-1-naphthol

Names

[ CAS No. ]:
711-79-5

[ Name ]:
2-Acetyl-1-naphthol

[Synonym ]:
MFCD00003963
1-(1-hydroxynaphthalen-2-yl)ethanone
EINECS 211-918-8

Chemical & Physical Properties

[ Density]:
1.213g/cm3

[ Boiling Point ]:
334.9ºC at 760 mmHg

[ Melting Point ]:
97-100ºC

[ Molecular Formula ]:
C₁₂H₁₀O₂

[ Molecular Weight ]:
186.20700

[ Flash Point ]:
142.4ºC

[ Exact Mass ]:
186.06800

[ PSA ]:
37.30000

[ LogP ]:
2.74800

[ Appearance of Characters ]:
Crystalline Powder | Yellow

[ Index of Refraction ]:
1.65

[ Water Solubility ]:
Insoluble in water.

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.

Bioorg. Med. Chem. 17 , 5219-28, (2009)

In the light of known HDAC inhibitors, 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop ...

Modulation of photophysics and photodynamics of 1'-hydroxy-2'-acetonaphthone (HAN) in bile salt aggregates: a study of polarity and nanoconfinement effects.

J. Phys. Chem. B 116(30) , 8780-92, (2012)

The modulation of the photophysical properties of 1'-hydroxy-2'-acetonaphthone (HAN) upon encapsulation into the hydrophobic nanocavities of different bile salt aggregates has been investigated for th...

4-acetoxy-2-acetyl-1-naphthol
5-acetoxy-2-acetyl-1-naphthol
2-acetyl-4-methoxy-1-naphthol-p-tosylate
2-acetyl-7-bromo-4,8-dimethoxy-1-naphthol
2-acetyl-4,5,6,8-tetramethoxy-1-naphthol
2-acetyl-4-acetoxy-3,5,6,8-tetramethoxy-1-naphthol
3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanoyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylbutanoyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
5-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylcyclohexyl]formamido}pentanoic acid
3-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)furan-2-carbonyl]-3-azabicyclo[4.1.0]heptane-7-carboxylic acid
(2S)-1-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methylpentanoyl]-2-methylpyrrolidine-2-carboxylic acid
(2S)-1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3,3-dimethylbutanoyl]-2-methylpyrrolidine-2-carboxylic acid
Methyl 2-hydroxy-3-(6-methylpyridin-3-yl)propanoate
4-(N-ethyl-1-{3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-2-yl}formamido)butanoic acid
3-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3,3,3-trifluoropropanoyl}-1,3-thiazolidine-4-carboxylic acid

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