Carbamic acid,(4-phenyl-2-thiazolyl)-, 2,2,2-trichloroethyl ester (9CI)

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Names

[ CAS No. ]:
71119-10-3

[ Name ]:
Carbamic acid,(4-phenyl-2-thiazolyl)-, 2,2,2-trichloroethyl ester (9CI)

[Synonym ]:
Lotifazolum [INN-Latin]
4-Phenyl-2-(2',2',2'-trichloroethoxycarboxamido)thiazole
Lotifazol [INN-Spanish]
2,2,2-Trichloroethyl (4-phenyl-2-thiazolyl)carbamate
Lotifazole
F 1686
2,2,2-trichloroethyl(4-phenyl-1,3-thiazol-2-yl)carbamate

Chemical & Physical Properties

[ Density]:
1.545g/cm3

[ Molecular Formula ]:
C12H9Cl3N2O2S

[ Molecular Weight ]:
351.63600

[ Exact Mass ]:
349.94500

[ PSA ]:
79.46000

[ LogP ]:
4.80180

[ Index of Refraction ]:
1.644

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
FD0810000
CHEMICAL NAME :
Carbamic acid, (4-phenyl-2-thiazolyl)-, 2,2,2-trichloroethyl ester
CAS REGISTRY NUMBER :
71119-10-3
LAST UPDATED :
199406
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H9-Cl3-N2-O2-S
MOLECULAR WEIGHT :
351.64

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJIMDS International Journal of Immunopharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1979- Volume(issue)/page/year: 2,169,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
IJIMDS International Journal of Immunopharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1979- Volume(issue)/page/year: 2,169,1980

Related Compounds

  • [5-(Dimethylsulfamoyl)-1-ethylbenzimidazol-2-yl]methyl 3,6-dichloropyridine-2-carboxylate
  • 6-({4-chloro-N-[3-(7-methoxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)propanoyl]phenylalanyl}amino)hexanoic acid
  • C36H44N2O7S
  • 5-tert-butyl-N-[(1-ethyl-3-methyl-1H-pyrazol-4-yl)methyl]-4,5,6,7-tetrahydro-1,2-benzoxazole-3-carboxamide
  • 3-Methyl-5,5-bis(4-methylphenyl)-2,4-imidazolidinedione
  • [3,5-bis(difluoromethyl)-5-hydroxy-4,5-dihydro-1H-pyrazol-1-yl]{1-[(3-chloro-4-fluorophenoxy)methyl]-1H-pyrazol-3-yl}methanone
  • N-[1-[(3-Chlorophenoxy)methyl]-1H-pyrazol-4-yl]-1-ethyl-1H-pyrazole-4-sulfonamide
  • 2-[4-(4-Methoxyphenyl)-1-piperazinyl]-1-(1,2,3,4-tetrahydro-3-methyl-9H-carbazol-9-yl)ethanone
  • 2-Amino-4-methoxy-3-methylbenzoic acid ethyl ester
  • 2-(2,4-Dihydroxyphenyl)ethanimidamide
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