4-[6-(10-methyl-9H-acridin-9-yl)cyclohexen-1-yl]morpholine

Names

[ Name ]:
4-[6-(10-methyl-9H-acridin-9-yl)cyclohexen-1-yl]morpholine

[Synonym ]:
10-methyl-9-[2-(morpholin-4-yl)cyclohex-2-en-1-yl]-9,10-dihydroacridine
9,10-Dihydro-10-methyl-9-(2-(4-morpholinyl)-2-cyclohexen-1-yl)acridine
ACRIDINE,9,10-DIHYDRO-10-METHYL-9-(2-(4-MORPHOLINYL)-2-CYCLOHEXEN-1-YL)

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₈N₂O

[ Molecular Weight ]:
360.49200

[ Exact Mass ]:
360.22000

[ PSA ]:
15.71000

[ LogP ]:
4.91890

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR9085000

CHEMICAL NAME :: Acridine, 9,10-dihydro-10-methyl-9-(2-(4-morpholinyl)-2-cyclohe xen-1-yl)-

CAS REGISTRY NUMBER :: 71167-36-7

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C24-H28-N2-O

MOLECULAR WEIGHT :: 360.54

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 750 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - changes in motor activity (specific assay) Gastrointestinal - hypermotility, diarrhea

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 13,1037,1979

Related Compounds

4-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-5-yl]formamido}-2-methylbutanoic acid
(2R)-2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-5-yl]formamido}pentanoic acid
1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazole-5-carbonyl]-4-methoxypyrrolidine-3-carboxylic acid
4-(1-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-4-methyl-1,3-thiazol-5-yl}-N-methylformamido)butanoic acid
3-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazol-5-yl]formamido}-2-methoxypropanoic acid
1-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]methyl}cyclopentane-1-carboxylic acid
3-ethyl-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanoyl]pyrrolidine-3-carboxylic acid
2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]methyl}cyclopentane-1-carboxylic acid
3-cyclopropyl-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]propanoic acid
rac-2-[(1R,2S)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]cyclopentyl]acetic acid

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