Bromobimane

Names

[ CAS No. ]:
71418-44-5

[ Name ]:
Bromobimane

[Synonym ]:
MONOBROMOBIMANE
Monobromobimane
Bromobimane

Chemical & Physical Properties

[ Density]:
1.66g/cm3

[ Boiling Point ]:
327.8ºC at 760 mmHg

[ Melting Point ]:
152-154ºC

[ Molecular Formula ]:
C₁₀H₁₁BrN₂O₂

[ Molecular Weight ]:
271.11100

[ Flash Point ]:
152.1ºC

[ Exact Mass ]:
270.00000

[ PSA ]:
42.96000

[ LogP ]:
1.01710

[ Index of Refraction ]:
1.64

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethyl 2-methylacetoacetate
4-Chloro-3,4-dimethyl-2-pyrazolin-5-one
3,4-Dimethyl-5-pyrazolinone
syn-(Methyl,methyl)bimane
9,10-dioxa-syn-(hydroxymethyl,methyl)(methyl,methyl)bimane

DownStream

9,10-dioxa-syn-(1-propylthiomethyl,methyl)(methyl,methyl)bimane
syn-(Methyl,methyl)bimane
2-[(1,2,6-trimethyl-3,5-dioxopyrazolo[1,2-a]pyrazol-7-yl)methylsulfanyl]acetic acid
Monochlorobimane
BIMANE AMINE
9,10-dioxa-syn-(cyano,methyl)(methyl,methyl)bimane

Articles

Dieckol as a novel anti-proliferative and anti-angiogenic agent and computational anti-angiogenic activity evaluation.

Environ. Toxicol. Pharmacol. 39(1) , 259-70, (2015)

In the current study it was found that dieckol isolated from edible brown algae, Ecklonia cava (EC), as potent anti-proliferative and anti-angiogenic agent. Vascular endothelial growth factor (VEGF) i...

Mg2+-dependent conformational changes and product release during DNA-catalyzed RNA ligation monitored by Bimane fluorescence.

Nucleic Acids Res. 43(1) , 40-50, (2015)

Among the deoxyribozymes catalyzing the ligation of two RNA substrates, 7S11 generates a branched RNA containing a 2',5'-linkage. We have attached the small fluorogenic probe Bimane to the triphosphat...

Allosteric Activation of a G Protein-coupled Receptor with Cell-penetrating Receptor Mimetics.

J. Biol. Chem. 290 , 15785-98, (2015)

G protein-coupled receptors (GPCRs) are remarkably versatile signaling systems that are activated by a large number of different agonists on the outside of the cell. However, the inside surface of the...

2-[(2-Methoxy-5-nitrophenoxy)methyl]oxirane
5-((4-Benzylpiperidin-1-yl)(p-tolyl)methyl)-2-(furan-2-yl)thiazolo[3,2-b][1,2,4]triazol-6-ol
5-((3,5-Dimethylpiperidin-1-yl)(p-tolyl)methyl)-2-(furan-2-yl)thiazolo[3,2-b][1,2,4]triazol-6-ol
Furan-2-yl(4-((2-(furan-2-yl)-6-hydroxythiazolo[3,2-b][1,2,4]triazol-5-yl)(p-tolyl)methyl)piperazin-1-yl)methanone
5-((3,4-dihydroisoquinolin-2(1H)-yl)(p-tolyl)methyl)-2-(furan-2-yl)thiazolo[3,2-b][1,2,4]triazol-6-ol
1-(4-((2-(Furan-2-yl)-6-hydroxythiazolo[3,2-b][1,2,4]triazol-5-yl)(p-tolyl)methyl)piperazin-1-yl)ethanone
Ethyl 1-((2,4-dichlorophenyl)(2-(furan-2-yl)-6-hydroxythiazolo[3,2-b][1,2,4]triazol-5-yl)methyl)piperidine-4-carboxylate
3,5-dichloro-N-(6-methanesulfonyl-1,3-benzothiazol-2-yl)-4-methoxybenzamide
3-allyl-8-(2-methoxyethyl)-1,7-dimethyl-1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione
ethyl 2-(2-((4-oxo-4H-pyrido[1,2-a][1,3,5]triazin-2-yl)thio)acetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate

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